374067-98-8

Basic information

• Product Name: 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate
• Synonyms: 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate
• CAS NO: 374067-98-8
• Molecular Weight: 698.594
• Mol File: 374067-98-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate(374067-98-8)
• EPA Substance Registry System: 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate(374067-98-8)

Safety Data

• Hazardous Substances Data: 374067-98-8(Hazardous Substances Data)

Upstream product

• 245118-91-6 N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 245118-90-5 4-[1,1-dimethyl-2-(tetrahydro-pyran-2-yloxy)-ethyl]-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide 
• 245118-89-2 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 245118-94-9 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 
• 374067-95-5 2-methyl-2-(4-sulfamoylphenyl)propionic acid 
• 374067-96-6 4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 
• 2901-13-5 ethyl 2-methyl-2-phenylpropionate 
• 108-24-7 acetic anhydride 
• 169679-53-2 N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-(4-methylphenyl)-4-pyrimidinyl]-4-(2-hydroxy-1,1-dimethylethyl)-benzenesulfonamide 
• 321565-78-0 ethyl 2-(4-chlorosulfonylphenyl)-2-methylpropionate 
• 374067-94-4 ethyl 2-methyl-2-(4-sulfamoylphenyl)propionate 

Downstream Products

• 374068-00-5 2-(4-(N-(5-acetoxymethyl)phenyl-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-N-acetylsulfamoyl)phenyl)-2-methylpropyl acetate 
• 374067-99-9 2-(4-(N-acetyl-N-(5-((4-bromomethyl)phenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate 

Relevant articles and documents

Potent and selective ET-A antagonists. 2. Discovery and evaluation of potent and water soluble N-(6-(2-(Aryloxy)ethoxy)-4-pyrimidinyl) sulfonamide derivatives

In the preceding article, we outlined the discovery and structure-activity relationship of a potent and selective ETA receptor antagonist 1 and its related compounds. Metabolites of 1 having potent selective ETA receptor antagonist a