374067-95-5

Basic information

• Product Name: 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid
• Synonyms: 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid;4-(Aminosulfonyl)-a,a-dimethyl-benzeneacetic Acid;4-(Aminosulfonyl)-α,a-dimethyl-benzeneacetic Acid;4-(AMinosulfonyl)-α,α-diMethyl-benzeneacetic Acid
• CAS NO: 374067-95-5
• Molecular Formula: C₁₀H₁₃NO₄S
• Molecular Weight: 0
• Product Categories: Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds
• Mol File: 374067-95-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 165-175°C
• Boiling Point: 443.725°C at 760 mmHg
• Flash Point: 222.157°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Refrigerator
• Solubility: DMSO, Methanol
• CAS DataBase Reference: 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid(374067-95-5)
• EPA Substance Registry System: 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid(374067-95-5)

Safety Data

• Hazardous Substances Data: 374067-95-5(Hazardous Substances Data)

Usage

Description

2-Methyl-2-(4-sulfamoylphenyl)propionic Acid, with the CAS number 374067-95-5, is an organic compound characterized by its off-white powder appearance. It is primarily utilized in the field of organic synthesis, where its unique chemical structure contributes to the creation of various complex molecules and pharmaceuticals.

Uses

Used in Organic Synthesis:
2-Methyl-2-(4-sulfamoylphenyl)propionic Acid is used as a synthetic building block for the development of new organic compounds. Its chemical properties allow it to be a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid is used as an intermediate in the synthesis of various drugs. Its unique structure and reactivity make it a valuable asset in the development of new medications, potentially leading to the creation of novel therapeutic agents.
Used in Research and Development:
2-Methyl-2-(4-sulfamoylphenyl)propionic Acid is also employed in research and development settings, where it can be used to study the properties and behavior of similar compounds. This knowledge can then be applied to the design and synthesis of new molecules with specific applications in various industries.
Overall, 2-Methyl-2-(4-sulfamoylphenyl)propionic Acid is a valuable compound in the fields of organic synthesis, pharmaceuticals, and research, with its off-white powder form and unique chemical properties making it a versatile and essential component in the development of new molecules and therapeutic agents.

InChI:InChI=1/C10H13NO4S/c1-10(2,9(12)13)7-3-5-8(6-4-7)16(11,14)15/h3-6H,1-2H3,(H,12,13)(H2,11,14,15)

Upstream product

• 57625-74-8 methyl 2-methyl-2-phenylpropionate 
• 321565-78-0 ethyl 2-(4-chlorosulfonylphenyl)-2-methylpropionate 
• 374067-94-4 ethyl 2-methyl-2-(4-sulfamoylphenyl)propionate 
• 2901-13-5 ethyl 2-methyl-2-phenylpropionate 

Downstream Products

• 374067-97-7 2-(4-(N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropionic acid 
• 374067-96-6 4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 
• 245118-94-9 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(2-hydroxy-1,1-dimethylethyl)benzenesulfonamide 
• 169677-37-6 2-(4-(N-(6-chloro-(2-hydroxyethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropionic acid 
• 245118-89-2 N-(6-chloro-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 169679-53-2 N-[6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-5-(4-methylphenyl)-4-pyrimidinyl]-4-(2-hydroxy-1,1-dimethylethyl)-benzenesulfonamide 
• 245118-90-5 4-[1,1-dimethyl-2-(tetrahydro-pyran-2-yloxy)-ethyl]-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide 
• 374067-98-8 2-(4-(N-acetyl-N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate 
• 374067-99-9 2-(4-(N-acetyl-N-(5-((4-bromomethyl)phenyl)-6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)sulfamoyl)phenyl)-2-methylpropyl acetate 
• 245118-91-6 N-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-5-(4-methylphenyl)-4-pyrimidinyl)-4-(1,1-dimethyl-2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl)benzenesulfonamide 
• 374068-00-5 2-(4-(N-(5-acetoxymethyl)phenyl-(6-(2-((5-bromo-2-pyrimidinyl)oxy)ethoxy)-4-pyrimidinyl)-N-acetylsulfamoyl)phenyl)-2-methylpropyl acetate 
• 253688-62-9 Ro 64-1056 

Relevant articles and documents

Chemical synthesis method of bosentan metabolite

The invention discloses a chemical synthesis method of bosentan metabolite. According to the method disclosed by the invention, the bosentan metabolite is obtained from 2, 2-dimethyl methyl phenylacetate through six-step reaction. The whole preparation method is high in operability, high in preparation efficiency and low in production cost, and industrial mass production can be achieved. The bosentan metabolite prepared by the invention is higher in bioavailability, can directly play a role in resisting hypertension, and is lower in adverse reaction.