37674-72-9Relevant articles and documents
A Novel and Convenient Mercury(II) Mediated Synthesis of Chroman-4-ones
Gopalsamy, Ariamala,Balasubramanian, K. K.
, p. 34 - 35 (1988)
A simple route to chroman-4-ones from γ-bromopropynyl aryl ethers (1) using mercury(II) trifluoroacetate as a catalyst is described.
Synthesis and antimicrobial activity of 2-(4-phenyl-2h-chromen-3-yl)-1h-benzo[d]imidazole
DASARI, RAMACHANDRAIAH,THALARI, GANGADHAR,YERRABELLY, JAYAPRAKASH RAO,CHITNENI, PRASAD RAO
, p. 1723 - 1728 (2021/07/31)
A new series of 4-phenyl-2H-chromene-3-benzimidazoles (8a-o) were synthesized by the condensation of 4-phenyl-2H-chromene-3- carbaldehyde with o-phenylene diamines. The products were purified through column chromatography and structures of these compounds were characterized by IR, 1H & 13C NMR and mass spectral data. All the final compounds were screened for their antimicrobial activity and their efficacy were matched with ciprofloxacin. Five compounds (8b, 8d, 8i, 8l and 8o) were found to be most effective compounds of this series and with activities improved than ciprofloxacin under the tested conditions.
Facile access to chiral 4-substituted chromanes through Rh-catalyzed asymmetric hydrogenation
Tao, Lin,Zhao, Qingyang,Zhang, Xumu,Dong, Xiu-Qin
, p. 1859 - 1862 (2020/01/21)
Rh/ZhaoPhos-catalyzed asymmetric hydrogenation of a series of (E)-2-(chroman-4-ylidene)acetates was successfully developed to prepare various chiral 4-substituted chromanes with high yields and excellent enantioselectivities (up to 99percent yield, 98percent ee). Moreover, the gram-scale hydrogenation could be performed well in the presence of 0.02 molpercent catalyst loading (TON = 5000), the hydrogenation product was easily converted to access other important compounds, which demonstrated the synthetic utility of this asymmetric catalytic methodology.
