3835-64-1

Basic information

• Product Name: 2,2-DIMETHYL-1-PHENYL-1-PROPANOL
• Synonyms: AURORA KA-6954;2,2-DIMETHYL-1-PHENYL-1-PROPANOL;Benzenemethanol, alpha-(1,1-dimethylethyl)-;α-(1,1-Dimethylethyl)benzenemethanol;α-tert-Butylbenzenemethanol;α-tert-Butylbenzyl alcohol;2,2-dimethyl-1-phenyl-propan-1-ol;2,2-dimethyl-1-phenylpropan-1-ol
• CAS NO: 3835-64-1
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.24
• Product Categories: Alcohols;C9 to C30;Oxygen Compounds
• Mol File: 3835-64-1.mol
• Article Data: 269

Chemical Properties

• Melting Point: 43-45 °C(lit.)
• Boiling Point: 90 °C5 mm Hg(lit.)
• Flash Point: 206 °F
• Appearance: /
• Density: 0.9197 (rough estimate)
• Vapor Pressure: 0.0567mmHg at 25°C
• Refractive Index: 1.5179 (estimate)
• PKA: 14.43±0.20(Predicted)
• CAS DataBase Reference: 2,2-DIMETHYL-1-PHENYL-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-1-PHENYL-1-PROPANOL(3835-64-1)
• EPA Substance Registry System: 2,2-DIMETHYL-1-PHENYL-1-PROPANOL(3835-64-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3835-64-1(Hazardous Substances Data)

Usage

Description

2,2-DIMETHYL-1-PHENYL-1-PROPANOL is an organic compound that has been utilized in various chemical reactions and processes. It is known for its unique properties and reactivity, which make it a valuable component in the synthesis of other compounds.

Uses

Used in Chemical Synthesis:
2,2-DIMETHYL-1-PHENYL-1-PROPANOL is used as a starting material for the preparation of various chemical compounds. Its unique structure allows for a range of reactions, making it a versatile component in the synthesis of different molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2-DIMETHYL-1-PHENYL-1-PROPANOL is used as an intermediate in the synthesis of drugs. Its reactivity and compatibility with various catalysts make it a valuable asset in the development of new medications.
Used in Catalyst Research:
2,2-DIMETHYL-1-PHENYL-1-PROPANOL has been employed in the study of catalysts, such as Raney nickel and Raney cobalt, for transfer hydrogenolysis reactions. This research contributes to the understanding of catalyst behavior and the optimization of reaction conditions.
Used in Electrochemical Processes:
2,2-DIMETHYL-1-PHENYL-1-PROPANOL has also been used in the investigation of electrochemical processes, such as kinetic resolution using a lead dioxide anode modified with poly-S-valine grafted onto a polypyrrole film. This research helps in the development of more efficient and selective electrochemical methods.
Used in Oxidation Reactions:
2,2-DIMETHYL-1-PHENYL-1-PROPANOL has been studied in the context of efficient Cu(I)-catalyzed oxidation reactions with di-tert-butyldiaziridinone as an oxidant. This research contributes to the advancement of oxidation techniques under mild conditions, which is crucial for the synthesis of various organic compounds.

InChI:InChI=1/C11H16O/c1-11(2,3)10(12)9-7-5-4-6-8-9/h4-8,10,12H,1-3H3

Upstream product

• 938-16-9 2,2-dimethylpropiophenone 
• 1068-56-0 isopropylmagnesium iodide 
• 920-39-8 isopropylmagnesium bromide 
• 677-22-5 tert-butylmagnesium chloride 
• 10557-57-0 propylmagnesium iodide 
• 100-52-7 benzaldehyde 
• 507-20-0 tertiary butyl chloride 
• 64-19-7 acetic acid 
• 611-70-1 phenyl isopropyl ketone 
• 934-56-5 trimethyl(phenyl)stannane 
• 630-19-3 pivalaldehyde 
• 775-12-2 diphenylsilane 
• 123-11-5 4-methoxy-benzaldehyde 
• 76261-67-1 (2,2-Dimethyl-1-phenyl-propoxy)-diphenyl-silane 

Downstream Products

• 70712-85-5 1-phenyl-2,2-dimethyl-1-propyl bromide 
• 938-16-9 2,2-dimethylpropiophenone 
• 23439-91-0 (1S)-2,2-dimethyl-1-phenyl-1-propanol 
• 1688-17-1 1-chloro-2,2-dimethyl-1-phenylpropane 
• 70712-76-4 2,2-Dimethyl-1-(4-neopentylphenyl)-1-phenylpropan 
• 17498-71-4 3-methyl-2-phenyl-1-butene 
• 769-57-3 α,β,β-trimethylstyrene 
• 53172-83-1 2-methyl-3-phenyl-1-butene 
• 3280-08-8 2-methyl-3-phenyl-butan-2-ol 
• 61986-33-2 2,2-dimethyl-1-(p-nitrophenyl)propan-1-ol 
• 61986-34-3 (R/S)-1-(2-nitrophenyl)-2,2-dimethyl-1-propanol 
• 15972-13-1 1-Cyclohexyl-2,2-dimethyl-1-propanol 
• 61501-04-0 2,2-dimethyl-1-phenyl-propylamine 
• 22876-56-8 1,2-dimethyl-1-phenyl-propylamine 

Relevant articles and documents

Developments in transfer hydrogenations of aromatic ketones catalyzed by boron compounds

Boron complexes BL1 and BL2 were prepared from O-donor ligands, 2,2′-(1E,1′E)-(ethane-1,2-diylbis(azan-1-yl-1-ylidene))bis(methane-1-yl-1-ylidene)diphenol (L1) and 2,2′-(propane-1,3-diylbis(azan-1-yl-1-ylidene))bis(methane-1-yl-1-ylidene)diphenol (L2). The complexes were fully characterized by 1H and 13C NMR, LC-MS/MS, TGA/DTA, UV-Vis, elemental analysis, SEM, and FTIR. The transfer hydrogenation of acetophenone derivatives was investigated by the boron complexes in the presence of isoPrOH, as the hydrogen source, under basic condition with NaOH. The results showed that the boron complexes were promising catalytic precursors for transfer hydrogenation of aromatic ketones in 0.1?M isoPrOH solution (up to 99%). Both steric and electronic factors of this class of molecules had a significant impact on the catalytic properties.

Enantioselective hydrogen transfer reactions from propan-2-ol to ketones catalyzed by pentacoordinate iridium(I) complexes with chiral Schiff bases

Some diastereoisomeric pentacoordinate complexes of the type *)I> (COD=cis,cis-1,5-cyclooctadiene; NNR*=2-pyridinal-1-phenylethylimine (PPEI) (I), 2-acetylpyridine-1-phenylethylimine (APPEI) (II)) have been synthesized.Th

Preparation of catechol boronate esters enabled by N → B dative bond as efficient, stable, and green catalysts for the transfer hydrogenation of various ketones

A series of new structurally related catechol boronate esters enabled by N → B dative bond of general composition (B1-B4) and (B1N-B4N) were designed and synthesized for the transfer hydrogenation of various ket

PNO ligand containing planar chiral ferrocene and application thereof

The invention discloses a PNO ligand containing planar chiral ferrocene and application thereof. The PNO ligand containing planar chiral ferrocene is a planar chiral ferrocene-containing and phenol-containing PNO ligand as shown in a general formula (I) or (II) which is described in the specification, or a planar chiral ferrocene-containing and aryl-phosphoric-acid-containingPNO ligand containing as shown in a general formula (III) or (IV) which is described in the specification, or a planar chiral ferrocene-containing and carbon-chiral-phenol-containingPNO ligand as shown in a general formula (V) or (VI) which is described in the specification. The invention provides tridentate PNO ligands and processes for their complexation with transition metal salts or transition metal complexes; the introduction of salicylaldehyde and derivatives thereof, which are simple and easy to obtain, enables the ligands to have a bifunctionalization effect, and -OH in a formed catalyst has stronger acidity and is beneficial to combination with N/O in polar double bonds. Therefore, due to the bifunctionalization effect of the catalyst, the interaction between the catalyst and a substrate can be greatly improved, so a reaction can obtain higher catalytic activity and stereoselectivity.