38365-51-4

Basic information

• Product Name: 1-Chloro-4-(2,2-dibromocyclopropyl)benzene
• Synonyms: 1-Chloro-4-(2,2-dibromocyclopropyl)benzene
• CAS NO: 38365-51-4
• Molecular Formula: C₉H₇Br₂Cl
• Molecular Weight: 310.41288
• Mol File: 38365-51-4.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 1-Chloro-4-(2,2-dibromocyclopropyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-4-(2,2-dibromocyclopropyl)benzene(38365-51-4)
• EPA Substance Registry System: 1-Chloro-4-(2,2-dibromocyclopropyl)benzene(38365-51-4)

Safety Data

• Hazardous Substances Data: 38365-51-4(Hazardous Substances Data)

Usage

General Description

1-Chloro-4-(2,2-dibromocyclopropyl)benzene is a chemical compound with the molecular formula C9H6Br2Cl. It is a chlorinated derivative of a dibromocyclopropane compound. This chemical is a white to light yellow crystalline solid with a molecular weight of 275.450 g/mol. It is primarily used as a building block in organic synthesis, particularly in the production of different types of pharmaceuticals and agrochemicals. The compound is also used in the manufacturing of various materials and substances, such as polymers and plastics. It is important to handle 1-Chloro-4-(2,2-dibromocyclopropyl)benzene with caution, as it can be toxic and harmful if not used properly.

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 1073-67-2 4-vinylbenzyl chloride 
• 75-25-2 Bromoform 

Downstream Products

• 1352954-09-6 1-chloro-4-(3,3-difluoroprop-1-en-2-yl)benzene 
• 1402235-32-8 2-(3-(4-chlorophenyl)prop-1-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1446696-28-1 (Z)-2-(1-(4-chlorophenyl)prop-1-en-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1600528-34-4 (E)-1,2-dichloro-3-(4-chlorophenyl)-2-propene 
• 1600528-31-1 (Z)-1-chloro-4-(2,3-dichloroprop-1-en-1-yl)benzene 
• 51725-92-9 5-bromo-3-(4-chlorophenyl)isoxazole 
• 1644189-11-6 N¹,N¹,N³,N³-tetrabenzyl-2-(4-chlorobenzylidene)propane-1,3-diamine 
• 1446696-23-6 4,4,5,5-tetramethyl-2-[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl]-1,3,2-dioxaborolane 
• 2749-98-6 4-chlorophenylallene 
• 143722-61-6 1-bromo-2-(p-chlorophenyl)cyclopropane 

Relevant articles and documents

Photoredox Catalyzed Sulfonylation of Multisubstituted Allenes with Ru(bpy)3Cl2 or Rhodamine B

A highly regio- and stereoselective sulfonylation of allenes was developed that provided direct access to α, β-substituted unsaturated sulfone. By means of visible-light photoredox catalysis, the free radicals produced by p-toluenesulfonic acid reacted with multisubstituted allenes to obtain Markovnikov-type vinyl sulfones with Ru(bpy)3Cl2 or Rhodamine B as photocatalyst. The yield of this reaction could reach up to 91%. A series of unsaturated sulfones would be used for further transformation to some valuable compounds.

Polymerization of Allenes by Using an Iron(II) β-Diketiminate Pre-Catalyst to Generate High Mn Polymers

Herein, we report an iron(II)-catalyzed polymerization of arylallenes. This reaction proceeds rapidly at room temperature in the presence of a hydride co-catalyst to generate polymers of weight up to Mn=189 000 Da. We have determined the polymer structure and chain length for a range of monomers through a combination of NMR, differential scanning calorimetry (DSC) and gel permeation chromatography (GPC) analysis. Mechanistically, we postulate that the co-catalyst does not react to form an iron(II) hydride in situ, but instead the chain growth is proceeding via a reactive Fe(III) species. We have also performed kinetic and isotopic experiments to further our understanding. The formation of a highly unusual 1,3-substituted cyclobutane side-product is also investigated.

Photoredox-Catalyzed α-Aminoalkylcarboxylation of Allenes with CO2

The photoredox-catalyzed α-aminoalkylcarboxylation of aryl allenes with CO2 and N,N-dimethylanilines is reported for the first time (26 examples, up to 96% yield). In the case of electron-deficient allenes, good regioselectivity was observed (up to 94:6), exclusively generating kinetic products over thermodynamic products. This protocol is a novel synthetic method for highly functionalized β,γ-unsaturated γ-aminobutyric esters.