397243-76-4Relevant articles and documents
α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1
Becker, Daniel P,Barta, Thomas E,Bedell, Louis,DeCrescenzo, Gary,Freskos, John,Getman, Daniel P,Hockerman, Susan L,Li, Madeleine,Mehta, Pramod,Mischke, Brent,Munie, Grace E,Swearingen, Craig,Villamil, Clara I
, p. 2719 - 2722 (2007/10/03)
A series of α-amino-β-sulphone hydroxamates was prepared and evaluated for potency versus MMP-13 and selectivity versus MMP-1. Various substituents were employed on the α-amino group (P1 position), as well as different groups attached to the su
