40371-50-4 Usage
Description
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid, also known as (S)-(+)-Z-4-Amino-2-hydroxybutyric Acid, is an organic compound with the chemical formula C11H15NO4. It is an off-white crystalline powder that plays a significant role in the pharmaceutical industry due to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
(S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid is used as an intermediate in the synthesis of various pharmaceutical compounds, particularly aminoglycoside antibiotics. These antibiotics are known for their effectiveness against a wide range of bacterial infections, making this compound a valuable asset in the development of new drugs to combat antibiotic-resistant bacteria.
Used in Chemical Research:
As a versatile organic compound, (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid is also utilized in chemical research for the development of novel chemical entities and the study of various reaction mechanisms. Its unique structure allows for further functionalization and modification, enabling the creation of new molecules with potential applications in various fields, including medicine, agriculture, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 40371-50-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,7 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 40371-50:
(7*4)+(6*0)+(5*3)+(4*7)+(3*1)+(2*5)+(1*0)=84
84 % 10 = 4
So 40371-50-4 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO5/c14-10(11(15)16)6-7-13-12(17)18-8-9-4-2-1-3-5-9/h1-5,10,14H,6-8H2,(H,13,17)(H,15,16)/t10-/m1/s1
40371-50-4Relevant articles and documents
Amine-Functionalized Polylactide-PEG Copolymers
Arlcan, Mehmet Onur,Erdo?an, Sezgi,Mert, Olcay
, p. 2817 - 2830 (2018)
The formation of halogenated carboxylic acid intermediate followed by a ring-closing reaction led to amino-functionalized asymmetrical lactide monomer. PEG-based functional diblock and triblock polylactides were synthesized via a controlled ring-opening p
Design of novel antibiotics that bind to the ribosomal acyltransfer site
Haddad, Jalal,Kotra, Lakshmi P.,Llano-Sotelo, Beatriz,Kim, Choonkeun,Azucena Jr., Eduardo F.,Liu, Meizheng,Vakulenko, Sergei B.,Chow, Christine S.,Mobashery, Shahriar
, p. 3229 - 3237 (2007/10/03)
The structure of neamine bound to the A site of the bacterial ribosomal RNA was used in the design of novel aminoglycosides. The design took into account stereo and electronic contributions to interactions between RNA and aminoglycosides, as well as a ran
4-O-(2,3,5-Trideoxy-5-amino-α-D-pentofuranosyl)-6-O-aminoglycosyl-1,3-diaminocyclitois, methods for their preparation, pharmaceutical formulations thereof and their use as antibacterial agents
-
, (2008/06/13)
4-O-(2,3,5-Trideoxy-5-amino-α-D-pentofuranosyl)-6-O-aminoglycosyl-1,3-diaminocyclitols and 1-N-substituted derivatives thereof are described together with methods for their preparation and their use as antibacterial agents. Preferred are 1-N-(ω-amino-α-hydroxyalkanoyl)-[4-O-(2,3,5-trideoxy-5-amino-α-D-pentofuranosyl)-6-O-garosaminyl-2-deoxystreptamines], particularly the 1-N-(S-β-amino-α-hydroxypropionyl) derivatives, which are broad spectrum antibacterial agents.