40745-21-9

Basic information

• Product Name: dimethyl 2-cyclohexylidenesuccinate
• Synonyms: dimethyl 2-cyclohexylidenesuccinate
• CAS NO: 40745-21-9
• Molecular Weight: 226.273
• Mol File: 40745-21-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: dimethyl 2-cyclohexylidenesuccinate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-cyclohexylidenesuccinate(40745-21-9)
• EPA Substance Registry System: dimethyl 2-cyclohexylidenesuccinate(40745-21-9)

Safety Data

• Hazardous Substances Data: 40745-21-9(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 78-27-3 1-Ethynylcyclohexan-1-ol 
• 67-56-1 methanol 
• 108-94-1 cyclohexanone 
• 106-65-0 Dimethyl succinate 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 1122-60-7 1-nitrocyclohexane 
• 186581-53-3 diazomethane 
• 21985-20-6 3-cyclohexylidene-4-methoxy-4-oxobutanoic acid 
• 624-49-7 dimethylfumarate 

Downstream Products

• 79219-75-3 2-Cyclohexylidene-3-[1-p-tolyl-meth-(E)-ylidene]-succinic acid 4-methyl ester 
• 79219-92-4 2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 1-methyl ester 
• 79219-89-9 2-[1-(3-Chloro-phenyl)-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 1-methyl ester 
• 79219-72-0 2-[1-Benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 
• 79219-74-2 2-Cyclohexylidene-3-[1-(3,4-dimethoxy-phenyl)-meth-(E)-ylidene]-succinic acid 
• 79219-66-2 2-Cyclohexylidene-3-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-succinic acid 
• 79219-86-6 2-Cyclohexylidene-3-[1-(3-methoxy-phenyl)-meth-(E)-ylidene]-succinic acid 
• 79219-93-5 2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 
• 79219-91-3 2-[1-(3-Chloro-phenyl)-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 
• 79234-98-3 2-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-3-cyclohexylidene-succinic acid 
• 79219-77-5 2-Cyclohexylidene-3-[1-p-tolyl-meth-(E)-ylidene]-succinic acid 
• 79219-80-0 2-Cyclohexylidene-3-[1-phenyl-meth-(E)-ylidene]-succinic acid 
• 302331-86-8 2-cyclohexylidene-1,4-bis(methylsulfonyloxy)butane 
• 618447-12-4 2-cyclohexylidene-4-methoxy-4-oxobutanoic acid 

Relevant articles and documents

Phase-Transfer-Catalyzed Asymmetric Annulations of Alkyl Dihalides with Oxindoles: Unified Access to Chiral Spirocarbocyclic Oxindoles

A general phase-transfer-catalyzed asymmetric (n+1) (n = 4 or 5) annulation reaction, featuring the direct coupling of simple oxindoles with alkyl dihalides that are allylic/benzylic and non-allylic/benzylic, has been developed to provide previously inacc

Synthesis of (E)-3-alkylidenepyrrolidines by nucleophilic ring closure of (E)-2-alkylidene-1,4-diol derivatives

The synthesis of N-protected (E)-3-alkylidenepyrrolidines is reported. Nitroalkanes react with unsaturated 1,4-diesters and 1,4-keto esters, giving a tandem Michael addition/elimination of nitrous acid. The obtained 1,4-dicarbonyl compounds are reduced to the corresponding diols and then converted into their mesylates. Reaction of mesylates with benzylamine or 4-methylbenzenesulfonylamide affords the unsaturated pyrrolidines. Use of the sulfonylamide for the cyclization step has advantages over that of benzylamine, since it gives better yields of pyrrolidines, and furthermore, the benzenesulfonyl group can be efficiently removed in the presence of unsaturated bonds.

Stereochemistry of Cyclohexylidene(arylidene)succinates Formed in the Stobbe Condensation

The diacids obtained from acid-esters 1-cyclohexylidene-2-carbomethoxy-3-arylprop-2-ene-1-carboxylic acids (5a) and 1-cyclohexylidene-1-carbomethoxy-3-arylprop-2-ene-2-carboxylic acids (5b) are identical.This along with the physico-chemical studies clearl