41828-13-1

Basic information

• Product Name: tetralin-1-carbaldehyde
• Synonyms: tetralin-1-carbaldehyde;5,6,7,8-Tetrahydronaphthalene-1-carbaldehyde;1-NAPHTHALENECARBOXALDEHYDE, 5,6,7,8-TETRAHYDRO
• CAS NO: 41828-13-1
• Molecular Formula: C₁₁H₁₂O
• Molecular Weight: 160.2124
• Mol File: 41828-13-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 290.5°Cat760mmHg
• Flash Point: 158.7°C
• Appearance: /
• Density: 1.083g/cm³
• Vapor Pressure: 0.00206mmHg at 25°C
• Refractive Index: 1.588
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: tetralin-1-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: tetralin-1-carbaldehyde(41828-13-1)
• EPA Substance Registry System: tetralin-1-carbaldehyde(41828-13-1)

Safety Data

• Hazardous Substances Data: 41828-13-1(Hazardous Substances Data)

Usage

General Description

Tetralin-1-carbaldehyde, also known as 1-tetraldehyde, is a chemical compound with the molecular formula C10H10O. It is a colorless liquid with a floral odor, commonly used in the synthesis of pharmaceuticals and organic compounds. Tetralin-1-carbaldehyde is also utilized as a flavoring agent in the food industry due to its pleasant smell. Its aromatic properties make it a valuable ingredient in perfumes and fragrances. Additionally, it is a versatile intermediate in the production of agrochemicals and dyes. However, it is important to handle this compound with care as it may pose health hazards if inhaled, ingested, or comes into contact with skin and eyes.

InChI:InChI=1/C11H12O/c12-8-10-6-3-5-9-4-1-2-7-11(9)10/h3,5-6,8H,1-2,4,7H2

Upstream product

• 119-64-2 tetralin 
• 201230-82-2 carbon monoxide 
• 4885-02-3 Dichloromethyl methyl ether 
• 116451-84-4 (2E,9E)-Undeca-2,9-dienedial 

Downstream Products

• 1187976-31-3 (4,5-dihydrothiazol-2-yl)-[2-(3,5-dimethylphenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)-ethyl]-amine 
• 1187976-34-6 1-[2-(3,5-dimethylphenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)-ethyl]-3-(2-hydroxyethyl)-thiourea 
• 1187976-32-4 2-(3,5-dimethylphenyl)-1-(5,6,7,8-tetrahydronaphthalen-1-yl)-ethylamine 
• 1478-33-7 6-fluoro-2-<(5,6,7,8-tetrahydro-1-naphthalenyl)methyl>benzoic acid 
• 75489-92-8 4-(5,6,7,8-tetrahydro-[1]naphthyl)-butyric acid 
• 104761-67-3 4-fluoro-2-<(5,6,7,8-tetrahydro-1-naphthalenyl)methyl>benzoic acid 
• 3160-17-6 2-(5,6,7,8-tetrahydronaphthalene-1-yl)acetonitrile 
• 776-50-1 (1,2,3,4-tetrahydro-5-naphthyl)acetic acid 
• 35310-83-9 phenyl(5,6,7,8-tetrahydronaphthalen-1-yl)methanone 
• 4242-18-6 5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid 
• 856198-59-9 (+/-)-Hydroxy-phenyl-(5.6.7.8-tetrahydro-naphthyl-⁽¹⁾)-methan 
• 41790-30-1 (5,6,7,8-tetrahydronaphthalene-1-yl)methanol 
• 104778-46-3 5-fluoro-3-(5,6,7,8-tetrahydro-1-naphthalenyl)-1(3H)-isobenzofuranone 

Relevant articles and documents

BCL-2 INHIBITOR

Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.

Formylation of Aromatic Compounds with CO in HSO3F-SbF5 under Atmospheric Pressure

The formylation of aromatic compounds such as benzene, toluene, xylenes, mesitylene, indan, tetralin, fluorobenzene, chlorobenzene, and bromobenzene was carried out in HSO3F-SbF5 under atmospheric CO pressure at 0 deg C.In HSO3F-SbF5, both formylation and sulfonation took place to give formyl and sulfonyl compounds.In the case of alkylbenzenes, including toluene, xylenes, mesitylene, and tetralin, formylalkylbenzenesulfonyl fluorides, new compounds, were obtained by a one-pot reaction as well as alkylbenzaldehydes, alkylbenzenesulfonyl fluorides, and bis(alkylphenyl) sulfones.The direct introduction of a formyl and sulfonyl group was achieved in alkylbenzenes.The reaction path of the new compounds is a two-step reaction comprised of formylation as the first step and sulfonation as the second step.The product composition was strongly dependent on the acid strength of the HSO3F-SbF5 systems.The formyl compounds became predominant with increasing acidity of the HSO3F-SbF5 system.On the other hand, only sulfonyl compounds were produced when the acidity of the HSO3F-SbF5 system was low.