4461-38-5 Usage
Description
4-Methanesulfonylbenzamide, also known as 4-methylsulfonylbenzamide, is a chemical compound with the molecular formula C8H9NO3S. It is a white to pale brown solid that is highly soluble in water. This versatile chemical is commonly used as an intermediate in the synthesis of various organic compounds and pharmaceuticals, and is known for its anti-inflammatory and analgesic properties.
Uses
Used in Pharmaceutical Industry:
4-Methanesulfonylbenzamide is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of non-steroidal anti-inflammatory drugs (NSAIDs), providing relief from inflammation and pain.
Used in Agrochemical Industry:
In the agrochemical sector, 4-methanesulfonylbenzamide is used as a building block in the production of pesticides, playing a crucial role in the development of compounds that protect crops from pests and diseases.
Used in Material Science:
4-Methanesulfonylbenzamide is utilized in the synthesis of dyes and rubber chemicals within the material science industry, contributing to the creation of a wide range of products with various applications, from textiles to industrial materials.
Check Digit Verification of cas no
The CAS Registry Mumber 4461-38-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,6 and 1 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4461-38:
(6*4)+(5*4)+(4*6)+(3*1)+(2*3)+(1*8)=85
85 % 10 = 5
So 4461-38-5 is a valid CAS Registry Number.
4461-38-5Relevant articles and documents
Direct Transformation of Ethylarenes into Primary Aromatic Amides with N -Bromosuccinimide and I2-Aqueous NH3
Shimokawa, Shohei,Kawagoe, Yuhsuke,Moriyama, Katsuhiko,Togo, Hideo
supporting information, p. 784 - 787 (2016/03/01)
A variety of ethylarenes were converted into the corresponding primary aromatic amides in good yields via treatment with N-bromosuccinimide in the presence of a catalytic amount of 2,2′-azobis(isobutyronitrile) in a mixture of ethyl acetate and water, acetonitrile and water, or chloroform and water, followed by reaction with molecular iodine and aq NH3 in one pot. It was found that aryl α-bromomethyl ketones and/or aryl methyl ketones were formed at the first reaction step and their iodoform-type reaction occurred at the second reaction step to provide primary aromatic amides. The present reaction is a useful and practical transition-metal-free method for the preparation of primary aromatic amides from ethylarenes. (Chemical Equation Presented).
Chemoselective oxidations in water of functional groups
Fringuelli,Pellegrino,Piermatti,Pizzo
, p. 2665 - 2673 (2007/10/02)
The organic functional groups, formyl, cyano, hydroxymethyl and methyl sulfenyl, are oxidized with high yields in water only by using TBHP and controlling the pH of the reaction medium. In the presence of (CTA)2SO4, the oxidation of the easily oxidizable sulfide group is prevented and a highly chemoselective process is obtained. The role of the surfactant is discussed.