449187-71-7

Basic information

• Product Name: 6-chloro-2-(4-fluoro-phenyl)-imidazo[2,1-a]phthalazine
• Synonyms: 6-chloro-2-(4-fluoro-phenyl)-imidazo[2,1-a]phthalazine
• CAS NO: 449187-71-7
• Molecular Weight: 297.719
• Mol File: 449187-71-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-(4-fluoro-phenyl)-imidazo[2,1-a]phthalazine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(4-fluoro-phenyl)-imidazo[2,1-a]phthalazine(449187-71-7)
• EPA Substance Registry System: 6-chloro-2-(4-fluoro-phenyl)-imidazo[2,1-a]phthalazine(449187-71-7)

Safety Data

• Hazardous Substances Data: 449187-71-7(Hazardous Substances Data)

Upstream product

• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 13580-86-4 4-chlorophthalazin-1-ylamine 

Downstream Products

• 449187-73-9 6-chloro-2-(4-fluoro-phenyl)-3-iodo-imidazo[2,1-a]phthalazine 

Relevant articles and documents

Synthesis of Imidazo[2,1-a]phthalazines, Potential Inhibitors of p38 MAP Kinase. Prediction of Binding Affinities of Protein Ligands

Based upon molecular modeling, the pharmacophore of potential inhibitors of p38 MAPK (mitogen-activated protein kinases) is discussed and the predictive binding affinities are calculated. Synthesis of original diarylimidazo[2,1-a]phthalazines obtained by