469-28-3

Basic information

• Product Name: 1,4-bis(3,4-dimethoxyphenyl)dihydro-1H,3H-furo[3,4-c]furan-3a(4H)-ol
• Synonyms: 1H,3H-furo[3,4-c]furan-3a(4H)-ol, 1,4-bis(3,4-dimethoxyphenyl)dihydro-
• CAS NO: 469-28-3
• Molecular Formula: C₂₂H₂₆O₇
• Molecular Weight: 402.4376
• Mol File: 469-28-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 560.3°C at 760 mmHg
• Flash Point: 292.7°C
• Density: 1.253g/cm³
• Vapor Pressure: 2.17E-13mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: 1,4-bis(3,4-dimethoxyphenyl)dihydro-1H,3H-furo[3,4-c]furan-3a(4H)-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(3,4-dimethoxyphenyl)dihydro-1H,3H-furo[3,4-c]furan-3a(4H)-ol(469-28-3)
• EPA Substance Registry System: 1,4-bis(3,4-dimethoxyphenyl)dihydro-1H,3H-furo[3,4-c]furan-3a(4H)-ol(469-28-3)

Safety Data

• Hazardous Substances Data: 469-28-3(Hazardous Substances Data)

Usage

Molecular Structure

Consists of two 3,4-dimethoxyphenyl groups attached to a dihydrofurofuran ring

Family

Furofuranol family of compounds

Applications

Pharmaceuticals
Organic synthesis

Unique Properties

Suitable for use in a wide range of industries
Of interest to researchers and manufacturers

Derivation

Derived from the furofuranol family of compounds

Upstream product

• 20583-78-2 3,4-dimethoxy-cinnamic acid ethyl ester 
• 144918-24-1 (2R,3S)-3-(3,4-Dimethoxy-benzyloxymethyl)-2-(3,4-dimethoxy-phenyl)-4-methylene-tetrahydro-furan 
• 144918-21-8 ethyl 2-bromo-3-(3,4-dimethoxyphenyl)-3-(prop-2-ynyloxy)propanoate 
• 144918-22-9 ethyl rac-(2R,3R)-2-(3,4-dimethoxyphenyl)-4-methylenetetrahydrofuran-3-carboxylate 
• 144918-23-0 2-(3,4-dimethoxyphenyl)-3-(hydroxymethyl)-4-methylenetetrahydrofuran 
• 20583-78-2 ethyl (E)-3,4-dimethoxycinnamate 
• 144918-25-2 (4S,5R)-4-(3,4-Dimethoxy-benzyloxymethyl)-5-(3,4-dimethoxy-phenyl)-dihydro-furan-3-one 
• 96894-13-2 (+)-1-acetoxypinoresinol 
• 81426-15-5 (+)-1-acetoxypinoresinol 4''-O-methyl ether 
• 56-23-5 tetrachloromethane 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 7553-56-2 iodine 
• 186581-53-3 diazomethane 

Downstream Products

• 469-28-3 (+)-1-hydroxypinoresinol dimethyl ether 
• 1212517-63-9 (3aS)-1t,4c-bis-(2-bromo-4,5-dimethoxy-phenyl)-(6ac)-dihydro-furo[3,4-c]furan-3ar-ol 
• 1212517-63-9 (3aS)-1c,4c-bis-(2-bromo-4,5-dimethoxy-phenyl)-(6ac)-dihydro-furo[3,4-c]furan-3ar-ol 
• 126906-01-2 epidihydroneogmelinol 
• 172342-93-7 dihydroneogmelinol 
• 124281-57-8 (1S,2S,3S)-1-(3,4-Dimethoxy-phenyl)-2,3-bis-hydroxymethyl-6,7-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ol 
• 41328-89-6 (2S,3S)-2,3-diveratryl-butane-1,2,4-triol 
• 252726-89-9 (1R,8S,9R,12S)-8-(3,4-Dimethoxy-phenyl)-12-hydroxymethyl-4,5-dimethoxy-11-oxa-tricyclo[7.2.1.0^2,7]dodeca-2,4,6-trien-12-ol 
• 252726-94-6 (1S,8R,9S,12S)-8-(3,4-Dimethoxy-phenyl)-12-hydroxymethyl-4,5-dimethoxy-11-oxa-tricyclo[7.2.1.0^2,7]dodeca-2⁽⁷⁾,3,5-trien-12-ol 
• 124281-59-0 Acetic acid (1R,2R,3R)-3-acetoxymethyl-1-(3,4-dimethoxy-phenyl)-2-hydroxy-6,7-dimethoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl ester 
• 124281-62-5 C₂₇H₃₄O₈ 
• 124281-60-3 C₂₅H₃₂O₇ 
• 124281-61-4 [(4aR,10R,10aR)-10-(3,4-Dimethoxy-phenyl)-7,8-dimethoxy-2,2-dimethyl-4,4a,5,10-tetrahydro-naphtho[2,3-d][1,3]dioxin-10a-yl]-methanol 

Relevant articles and documents

Stereoselective Total Synthesis of (+/-)-Paulownin and (+/-)-Isogmelinol through Radical Annulation Route

A highly stereocontrolled synthesis of furofuran lignans, (+/-)-Paulownin (1a) and (+/-)-Isogmelinol (1b) is described involving intramolecular radical cyclisation as a key step.

Lignans from Bark of the Olea Plants. II

Four new lignans, (+)-1-acetoxypinoresinol-4'-β-D-glucoside (1), (+)-1-acetoxypinoresinol-4'-β-D-glucoside 4''-O-methyl ether (2), (+)-1-hydroxypinoresinol-1-β-D-glucoside (4) and (+)-fraxiresinol-1-β-D-glucoside (5), and a known lignan, (+)-1-hydroxypinoresinol-4'-β-D-glucoside (3), were isolated from the bark of Olea europaea L. and the bark of Olea africana MILL. (Olea europaea L. subsp. africana (MILL.) GREEN) (Oleaceae).Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence.The bark of Olea capensis L. did not yield any lignan glucosides.Keywords - Olea europaea; Olea africana; Olea capensis; Oleaceae; lignan; (+)-1-acetoxypinoresinol-4'-β-D-glucoside; (+)-1-acetoxypinoresinol-4'-β-D-glucoside 4''-O-methyl ether; (+)-1-hydroxypinoresinol-4'-β-D-glucoside; (+)-1-hydroxypinoresinol-1-β-D-glucoside; (+)-fraxiresinol-1-β-D-glucoside