480438-46-8 Usage
Description
2-Methoxybenzylmagnesium chloride is an organometallic compound that serves as a Grignard reagent in organic synthesis. It is characterized by its ability to form carbon-carbon and carbon-heteroatom bonds, making it a versatile and valuable tool in the synthesis of various organic compounds.
Uses
Used in Organic Synthesis:
2-Methoxybenzylmagnesium chloride is used as a Grignard reagent for the synthesis of complex organic molecules. Its application is particularly notable in the synthesis of (-)-Chamobtusin A, a natural product with potential biological activities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Methoxybenzylmagnesium chloride is utilized in the preparation of molybdenum and tungsten Alkylidene complexes with a tert-butylimido ligand. These complexes are of interest due to their potential applications in medicinal chemistry and the development of new therapeutic agents.
Overall, 2-Methoxybenzylmagnesium chloride is a valuable reagent in the fields of organic synthesis and pharmaceutical chemistry, contributing to the development of novel compounds and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 480438-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,0,4,3 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 480438-46:
(8*4)+(7*8)+(6*0)+(5*4)+(4*3)+(3*8)+(2*4)+(1*6)=158
158 % 10 = 8
So 480438-46-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H9O.ClH.Mg/c1-7-5-3-4-6-8(7)9-2;;/h3-6H,1H2,2H3;1H;/q;;+1/p-1/rC8H9ClMgO/c1-11-8-5-3-2-4-7(8)6-10-9/h2-5H,6H2,1H3
480438-46-8Relevant articles and documents
PIPERAZINE DERIVATIVES WHICH EXHIBIT ACTIVITY AS SEROTONIN AND NORADRENALINE RE-UPATKE INHIBITORS
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Page/Page column 54; 55, (2010/02/13)
A compound of formula (I), wherein R1 is H; R2 is aryl, het, C3-8cycloalkyl, C1-6alkyl, (CH2)zaryl or R4, wherein each of the cycloalkyl, aryl, het and R4 groups is op
CYCLISATION DE DIARYLALCANES EN MILIEU SUPERACIDE: SYNTHESE DE CETONES TRICYCLIQUES A METHYLE ANGULAIRE ET MECANISME DE LEUR ISOMERISATION
Berrier, C.,Jacquesy, J. C.,Gesson, J. P.,Renoux, A.
, p. 1983 - 1994 (2007/10/02)
Cyclisation of redily available diaryl-1,2 ethanes 1-4 proceeds in SbF5-HF at 0oC to yield tricyclic phenantrenones 5,6,7 and 11 bearing an angular methyl group.This process implies the electrophilic attack of the more basic aromatic ring, reacting through its disprotonated form (on the oxygen and the meta carbon atom) on the second aromatic ring.Isomerization of these primary products may be observed (to give ketones 8,9,10 from 3 and 12 from 4) and it has been demonstrated by the use of specifically deuterated 3d that it involves stereospecific 1,2 hydride (or deuteride) shifts, without exchange.
