4946-22-9

Basic information

• Product Name: 4-(dimethylamino)thiophenol
• Synonyms: 4-(Dimethylamino)benzenethiol;4-Mercapto-N,N-dimethylaniline;4-(Dimethylamino)thiophenol 4-Mercapto-N,N-dimethylaniline
• CAS NO: 4946-22-9
• Molecular Formula: C₈H₁₁NS
• Molecular Weight: 153.24
• Mol File: 4946-22-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 28.45°C
• Boiling Point: 260°C(lit.)
• Flash Point: 107.1°C
• Appearance: /
• Density: 1.0676 (rough estimate)
• Vapor Pressure: 0.0183mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 10.14±0.24(Predicted)
• CAS DataBase Reference: 4-(dimethylamino)thiophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(dimethylamino)thiophenol(4946-22-9)
• EPA Substance Registry System: 4-(dimethylamino)thiophenol(4946-22-9)

Safety Data

• RTECS: DC1575000
• Hazardous Substances Data: 4946-22-9(Hazardous Substances Data)

Usage

Description

4-(Dimethylamino)thiophenol is an organic compound characterized by the presence of a thiophene ring with a dimethylamino group at the 4-position. It is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
4-(Dimethylamino)thiophenol is used as a therapeutic agent for the treatment of various health conditions, including HBV and HDV infections, hypercholesterolemia, diabetes, and cancer. Its application is attributed to its ability to act as NTCP inhibitors, which can help in the treatment and management of these diseases.
Used in Hepatoprotection:
4-(Dimethylamino)thiophenol is used as a hepatoprotective agent, aiming to protect and improve liver function. Its application is based on its potential to ameliorate liver-related conditions and support overall liver health.
Used in Hypercholesterolemia Treatment:
4-(Dimethylamino)thiophenol is used as a cholesterol-lowering agent, particularly for the amelioration of hypercholesterolemia. Its application is due to its ability to help regulate cholesterol levels and improve cardiovascular health.
Used in Diabetes Management:
4-(Dimethylamino)thiophenol is used in the management of diabetes, as it may help in controlling blood sugar levels and improving overall metabolic health.
Used in Cancer Treatment:
4-(Dimethylamino)thiophenol is used as an anticancer agent, potentially inhibiting the growth and progression of cancer cells. Its application in this field is based on its ability to target and interfere with cancer-related pathways, making it a promising candidate for cancer treatment and research.

InChI:InChI=1/C8H11NS/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3

Upstream product

• 19715-49-2 4-(dimethylamino)benzenesulfonyl chloride 
• 925-89-3 Prop-1-en-1-thiol 
• 13190-50-6 4-dimethylaminophenyllithium 
• 160855-20-9 N-(N',N'-dimethyl-4-aminophenylthio)phthalimide 
• 571167-29-8 3-(4-N,N-dimethylaminophenyl)-sulfanyl-propionic acid methyl ester 
• 121-69-7 N,N-dimethyl-aniline 
• 854695-59-3 S-(4-dimethylamino-phenyl)-N,N'-diphenyl-isothiourea 
• 7664-41-7 ammonia 
• 500700-75-4 N,N-dimethyl-4-trichloromethylsulfanyl-aniline 
• 7732-18-5 water 
• 7664-93-9 sulfuric acid 
• 141-78-6 ethyl acetate 
• 7647-01-0 hydrogenchloride 
• 7152-80-9 4-(dimethylamino)benzenethiocyanate 

Downstream Products

• 63116-10-9 3-Nitro-4'-dimethylaminodiphenyldisulfid 
• 63116-13-2 4-(N,N-dimethylamino)phenyl 4'-nitrophenyl disulfide 
• 63116-21-2 4-Dimethylamino-4'-chlordiphenyldisulfid 
• 69064-55-7 C₂₅H₃₁N₃S₃ 
• 875737-07-8 methyl (E)-4-(4-dimethylaminophenylsulfanyl)-2-methyl-2-pentenoate 
• 220548-21-0 [((C₆H₅)3P)Au(SC₆H₄N(CH₃)2)] 
• 2388-51-4 p-dimethylaminoselenoanisole 
• 171364-78-6 (4-(N,N-dimethylamino)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 113121-53-2 6-p-dimethylaminophenylthio-3-methoxy-2-phenylimidazo<1,2-b>pyridazine 
• 698387-93-8 (2E,4E)-ethyl 6-(4-dimethylaminophenylsulfanyl)-4-methyl-2,4-heptadienoate 
• 875737-08-9 (E)-4-(4-dimethylaminophenylsulfanyl)-2-methyl-2-penten-1-ol 
• 57251-87-3 C₁₈H₂₄N₂S₂ 
• 77915-53-8 1,3-Bis-(4-dimethylamino-phenylsulfanyl)-propan-2-one 

Relevant articles and documents

Imposing Latency in Ruthenium Sulfoxide-Chelated Benzylidenes: Expanding Opportunities for Thermal and Photoactivation in Olefin Metathesis

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HISTONE DEACETYLASE INHIBITORS

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A monomer composition, stabilized against premature polymerization, comprising: a) an ethylenically unsaturated monomer or mixture of monomers polymerizable by free radical initiation, and b) an effective amount, sufficient to inhibit premature polymerization of component (a) of a mixture of: i) 1 to 99% by weight, based on the total weight of components (i) and (ii), of a mixture of at least one aromatic amine and at least one organic acid in a molar ratio of 10:1 to 1:10, and ii) 99 to 1% by weight, based on the total weight of components (i) and (ii), of at least one stable radical compound.