494799-66-5

Basic information

• Product Name: 3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine 7-oxide
• CAS NO: 494799-66-5
• Molecular Weight: 216.283
• Mol File: 494799-66-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine 7-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine 7-oxide(494799-66-5)
• EPA Substance Registry System: 3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine 7-oxide(494799-66-5)

Safety Data

• Hazardous Substances Data: 494799-66-5(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 271-63-6 7-Azaindole 
• 494799-64-3 3-cyclohexenyl-1H-pyrrolo[2,3-b]pyridine 
• 494799-65-4 3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 494799-71-2 3-cyclohexyl-1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid ethyl ester 
• 494799-70-1 2-bromo-3-cyclohexyl-1-methyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid ethyl ester 
• 494799-69-8 3-cyclohexyl-1-methyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylic acid ethyl ester 
• 494799-68-7 3-cyclohexyl-1-methyl-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile 
• 494799-67-6 3-cyclohexyl-1-methyl-1H-pyrrolo[2,3-b]pyridine 7-oxide 

Relevant articles and documents

Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds

Benzimidazole-based allosteric inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified to a variety of topologically related scaffolds. Replacement of the polar benzimidazole core by lipophilic indoles led to inhibitors with improved potency in the cell-based subgenomic HCV replicon system. Transposing the indole scaffold into a previously described series of benzimidazole-tryptophan amides generated the most potent inhibitors of HCV RNA replication in cell culture reported to date in this series (EC50 ～ 50 nM).