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494799-68-7

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494799-68-7 Usage

Molecular structure

1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 3-cyclohexyl-1-methylis a complex organic compound with a pyrrolopyridine derivative structure and a 3-cyclohexyl-1-methyl substituent.

Carbonitrile group

The presence of a carbonitrile group (C≡N) in the compound suggests potential reactivity and biological activity.

Medicinal chemistry applications

The compound may have applications in the field of medicinal chemistry due to its ability to potentially interact with biological targets and influence cellular processes.

Further investigation required

The specific properties and potential applications of 1H-Pyrrolo[2,3-b]pyridine-6-carbonitrile, 3-cyclohexyl-1-methylwould need to be further explored through experimental studies.

Check Digit Verification of cas no

The CAS Registry Mumber 494799-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,7,9 and 9 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 494799-68:
(8*4)+(7*9)+(6*4)+(5*7)+(4*9)+(3*9)+(2*6)+(1*8)=237
237 % 10 = 7
So 494799-68-7 is a valid CAS Registry Number.

494799-68-7Relevant articles and documents

Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds

Beaulieu, Pierre L.,Gillard, James,Bykowski, Darren,Brochu, Christian,Dansereau, Nathalie,Duceppe, Jean-Simon,Hache, Bruno,Jakalian, Araz,Lagace, Lisette,LaPlante, Steven,McKercher, Ginette,Moreau, Elaine,Perreault, Stephane,Stammers, Timothy,Thauvette, Louise,Warrington, Jeff,Kukolj, George

, p. 4987 - 4993 (2007/10/03)

Benzimidazole-based allosteric inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified to a variety of topologically related scaffolds. Replacement of the polar benzimidazole core by lipophilic indoles led to inhibitors with improved potency in the cell-based subgenomic HCV replicon system. Transposing the indole scaffold into a previously described series of benzimidazole-tryptophan amides generated the most potent inhibitors of HCV RNA replication in cell culture reported to date in this series (EC50 ~ 50 nM).

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