51575-77-0

Basic information

• Product Name: Oxazole, 2,2'-(1,4-phenylene)bis-
• CAS NO: 51575-77-0
• Molecular Formula: C12H8N2O2
• Molecular Weight: 212.208
• Mol File: 51575-77-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Oxazole, 2,2'-(1,4-phenylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 2,2'-(1,4-phenylene)bis-(51575-77-0)
• EPA Substance Registry System: Oxazole, 2,2'-(1,4-phenylene)bis-(51575-77-0)

Safety Data

• Hazardous Substances Data: 51575-77-0(Hazardous Substances Data)

Upstream product

• 41526-99-2 4-(4,5-dihydrooxazol-2-yl) benzonitrile 
• 623-26-7 terephthalonitrile 
• 106833-89-0 Terephthalic acid bis-N-(2-hydroxyethyl)amide acid sulfate 
• 18928-62-6 Terephthalic acid bis-N-(2-hydroxyethyl)amide 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 7426-75-7 1,4-bis(4,5-dihydro-2-oxazolyl)benzene 

Relevant articles and documents

DDQ-induced dehydrogenation of heterocycles for c-c double bond formation: Synthesis of 2-thiazoles and 2-oxazoles

Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.