7426-75-7

Basic information

• Product Name: 1,4-BIS(4,5-DIHYDRO-2-OXAZOLYL)BENZENE
• Synonyms: 1,4-BIS(4,5-DIHYDRO-2-OXAZOLYL)BENZENE;2,2'-(1,4-PHENYLENE)BIS(2-OXAZOLINE);1,4-Bisdihydrooxazolylbenzene;2,2'-(1,4-phenylene)bis[4,5-dihydrooxazole];2,2'-(1,4-phenylene)bis[4,5-dihydro-oxazol;1,4-Bis-(2-oxazolin-2-yl)-benzene;1,4-Bis(4,5-dihydrooxazole-2-yl)benzene;Einecs 231-066-0
• CAS NO: 7426-75-7
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.24
• EINECS: 231-066-0
• Mol File: 7426-75-7.mol
• Article Data: 19

Chemical Properties

• Melting Point: 146°C
• Boiling Point: 378.3 °C at 760 mmHg
• Flash Point: 148 °C
• Appearance: /
• Density: 1.32 g/cm³
• Vapor Pressure: 1.38E-05mmHg at 25°C
• Refractive Index: 1.646
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 4.55±0.50(Predicted)
• CAS DataBase Reference: 1,4-BIS(4,5-DIHYDRO-2-OXAZOLYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-BIS(4,5-DIHYDRO-2-OXAZOLYL)BENZENE(7426-75-7)
• EPA Substance Registry System: 1,4-BIS(4,5-DIHYDRO-2-OXAZOLYL)BENZENE(7426-75-7)

Safety Data

• Hazardous Substances Data: 7426-75-7(Hazardous Substances Data)

Usage

General Description

1,4-Bis(4,5-dihydro-2-oxazolyl)benzene is a chemical compound that is commonly used as a crosslinking agent in the production of thermoset polymers. It is a white crystalline solid with a molecular formula C16H18N2O2. 1,4-Bis(4,5-dihydro-2-oxazolyl)benzene is known for its ability to improve the mechanical and thermal properties of polymers, making them more resistant to heat and wear. It is also used as a stabilizer in the production of various plastic products, as well as in the synthesis of pharmaceuticals and agrochemicals. Additionally, it is used in the production of adhesives, coatings, and sealants. However, 1,4-Bis(4,5-dihydro-2-oxazolyl)benzene is known to be a skin and eye irritant and should be handled with caution.

InChI:InChI=1/C12H12N2O2/c1-2-10(12-14-6-8-16-12)4-3-9(1)11-13-5-7-15-11/h1-4H,5-8H2

Upstream product

• 926-39-6 sulfuric acid mono-(2-amino-ethyl ester) 
• 100-20-9 terephthaloyl chloride 
• 100-21-0 terephthalic acid 
• 141-43-5 ethanolamine 
• 106833-89-0 Terephthalic acid bis-N-(2-hydroxyethyl)amide acid sulfate 
• 623-26-7 terephthalonitrile 
• 41526-99-2 4-(4,5-dihydrooxazol-2-yl) benzonitrile 
• 636-09-9 diethyl terephthalate 
• 120-61-6 1,4-benzenedicarboxylic acid dimethyl ester 
• 623-27-8 terephthalaldehyde, 
• 18928-62-6 Terephthalic acid bis-N-(2-hydroxyethyl)amide 
• 40651-60-3 N,N'-bis-(2-chloro-ethyl)-terephthalamide 

Downstream Products

• 18126-24-4 2,2'-bisethanol 
• 51124-38-0 4,5,4',5'-tetrahydro-2,2'-cyclohexane-1,4-diyl-bis-oxazole 
• 51575-77-0 1,4-Phenylene-2,2'-bisoxazole 

Relevant articles and documents

A 2 - substituted oxazoline or 2 - substituted piperazine synthetic method (by machine translation)

The invention discloses a method for synthesizing 2 - substituted oxazoline or 2 - substituted oxazine new method, by nitrile and amino ethanol or 3 - amino - 1 - propanol as raw material, in the absence of solvent, can be used for the recycling of the sulfur to induce synthesis of 2 - substituted oxazoline and 2 - substituted piperazine. The method of the invention has low cost, simple reaction process, mild reaction conditions, the reaction time is short, the yield and the like, is suitable for the industrial generation. (by machine translation)

Copper N-Heterocyclic Carbene Complexes As Active Catalysts for the Synthesis of 2-Substituted Oxazolines from Nitriles and Aminoalcohols

The reaction between nitriles and aminoalcohols to access 2-substituted oxazolines was investigated. Using copper-NHC complexes, various nitriles were successfully converted into the corresponding oxazolines, under milder and less wasteful conditions than those of previously reported methods.

DDQ-induced dehydrogenation of heterocycles for c-c double bond formation: Synthesis of 2-thiazoles and 2-oxazoles

Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.