5256-60-0 Usage
Description
(6AR,9R)-7-METHYL-4,6,6A,7,8,9-HEXAHYDRO-INDOLO[4,3-FG]QUINOLINE-9-CARBOXYLIC ACID HYDRAZIDE is a hydrazide compound derived from indolo[4,3-fg]quinoline carboxylic acid, featuring a hydrazide functional group. It is recognized for its potential pharmacological and biological activities, such as anti-tumor, anti-inflammatory, and antibacterial properties. The unique chemical structure and properties of this compound render it a promising candidate for therapeutic applications in the medicinal and pharmaceutical fields.
Uses
Used in Pharmaceutical Industry:
(6AR,9R)-7-METHYL-4,6,6A,7,8,9-HEXAHYDRO-INDOLO[4,3-FG]QUINOLINE-9-CARBOXYLIC ACID HYDRAZIDE is used as a pharmaceutical compound for its potential therapeutic applications. Its anti-tumor, anti-inflammatory, and antibacterial properties make it a valuable asset in the development of new drugs to treat various diseases and conditions.
Used in Medicinal Research:
In the field of medicinal research, (6AR,9R)-7-METHYL-4,6,6A,7,8,9-HEXAHYDRO-INDOLO[4,3-FG]QUINOLINE-9-CARBOXYLIC ACID HYDRAZIDE is utilized as a key compound for exploring its potential in the treatment of cancer, inflammation, and bacterial infections. Its unique properties and structure offer opportunities for the development of novel therapeutic strategies and drug candidates.
Used in Drug Design and Development:
(6AR,9R)-7-METHYL-4,6,6A,7,8,9-HEXAHYDRO-INDOLO[4,3-FG]QUINOLINE-9-CARBOXYLIC ACID HYDRAZIDE serves as a crucial component in drug design and development, particularly for targeted therapies against specific diseases. Its versatile chemical structure allows for modifications and optimizations to enhance its efficacy, selectivity, and safety profile in various therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 5256-60-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,5 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5256-60:
(6*5)+(5*2)+(4*5)+(3*6)+(2*6)+(1*0)=90
90 % 10 = 0
So 5256-60-0 is a valid CAS Registry Number.
InChI:InChI=1/C16H10ClN3O/c17-10-7-5-9(6-8-10)14-13-11-3-1-2-4-12(11)18-15(13)16(21)20-19-14/h1-8,19H,(H,20,21)
5256-60-0Relevant articles and documents
Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst1 receptor
Troxler, Thomas,Enz, Albert,Hoyer, Daniel,Langenegger, Daniel,Neumann, Peter,Pfaeffli, Paul,Schoeffter, Philippe,Hurth, Konstanze
, p. 979 - 982 (2008/09/18)
Non-peptidic compounds containing the octahydro-indolo[4,3-fg]quinoline (ergoline) structural element have been optimized into derivatives with high affinity (pKd r sst1 > 9) and selectivity (>1000-fold for h sst1 over h sst2-h sst5) for the somatostatin sst1 receptor. In functional assays, these ergolines act as antagonists at human recombinant sst1 receptors. Pharmacokinetic studies in rodents reveal good oral bioavailability and brain penetration for some of these compounds.
