5381-93-1

Basic information

• Product Name: 2-Butanone, 4-hydroxy-4-phenyl-
• CAS NO: 5381-93-1
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• Mol File: 5381-93-1.mol
• Article Data: 304

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 4-hydroxy-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 4-hydroxy-4-phenyl-(5381-93-1)
• EPA Substance Registry System: 2-Butanone, 4-hydroxy-4-phenyl-(5381-93-1)

Safety Data

• Hazardous Substances Data: 5381-93-1(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 100-52-7 benzaldehyde 
• 26562-24-3 3-bromo-2-methoxypropene 
• 14230-31-0 1-triethylstannanyl-propan-2-one 
• 67-64-1 acetone 
• 7064-06-4 3-methyl-5-phenyl-4,5-dihydroisoxazole 
• 86864-46-2 C₂₉H₂₇NOS 
• 541-50-4 2-acetoacetic acid 
• 78-95-5 chloroacetone 
• 60609-82-7 trichloro<(1-methylethenyl)oxy>silane 
• 18312-45-3 propan-2-one O-acetyl oxime 
• 7450-22-8 Acetone O-trimethylsilyloxime 
• 93-91-4 1-phenylbutan-1,3-dione 
• 1118-84-9 allyl acetoacetate 

Downstream Products

• 100-52-7 benzaldehyde 
• 67-64-1 acetone 
• 97024-79-8 4-Aethoxycarbonyl-4-phenyl-butan-2-on 
• 65469-88-7 1-phenylbutane-1,3-diol 
• 1896-62-4 (E)-benzalacetone 
• 90026-44-1 anti-(1R,3S)-1-phenylbutane-1,3-diol 
• 118100-60-0 syn-(1R,3R)-1-phenylbutane-1,3-diol 
• 5381-93-1 (4S)-4-hydroxy-4-phenylbutan-2-one 
• 5381-93-1 (4R)-4-hydroxy-4-phenylbutan-2-one 
• 118918-39-1 (+)-(4R)-4-acetyloxy-4-phenyl-2-butanone 
• 106361-71-1 (4S,6S)-4-Hydroxy-4-methyl-6-phenyl-tetrahydro-pyran-2-one 
• 1159266-81-5 (1R,3S)-3-(benzylamino)-1-phenylbutan-1-ol 
• 81-81-2 warfarin 
• 103729-86-8 (+/-)-1-phenylbutane-1,3-diol 

Relevant articles and documents

Chiral Bipyridine Ligand with Flexible Molecular Recognition Site: Development and Application to Copper-Catalyzed Asymmetric Borylation of α,β-Unsaturated Ketones

A novel chiral bipyridine ligand bearing a flexible side chain with a molecular recognition site enables precise stereocontrol through the cooperative action of metal center and hydrogen bonds. This new chiral ligand was applied to the copper-catalyzed as

Defect-Engineered Chiral Metal-Organic Frameworks for Efficient Asymmetric Aldol Reaction

By employment of a mixed truncated chiral ligand synthetic strategy, a defect-engineered chiral metal-organic framework with hierarchical micro/mesoporous structure was prepared, and it exhibited efficient heterogeneous catalytic activity and enantioselectivity for asymmetric aldol reaction.

Chiral imidazolium prolinate salts as efficient synzymatic organocatalysts for the asymmetric aldol reaction

Chiral imidazolium L-prolinate salts, providing a complex network of supramolecular interaction in a chiral environment, have been studied as synzymatic catalytic systems. They are demonstrated to be green and efficient chiral organocatalysts for direct asymmetric aldol reactions at room temperature. The corresponding aldol products were obtained with moderate to good enantioselectivities. The influence of the presence of chirality in both the imidazolium cation and the prolinate anion on the transfer of chirality from the organocatalyst to the aldol product has been studied. Moreover, interesting match/mismatch situations have been observed regarding configuration of chirality of the two components through the analysis of results for organocatalysts derived from both enantiomers of prolinate (R/S) and the trans/cis isomers for the chiral fragment of the cation. This is associated with differences in the corresponding reaction rates but also to the different tendencies for the formation of aggregates, as evidenced by nonlinear effects studies (NLE). Excellent activities, selectivities, and enantioselectivities could be achieved by an appropriate selection of the structural elements at the cation and anion.