53951-44-3 Usage
Description
2-Ethyl-1,3-dioxolane-4-methanol is an organic compound characterized by its unique structure, which features a 1,3-dioxolane ring with an ethyl group at the 2nd position and a hydroxymethyl group at the 4th position. 2-Ethyl-1,3-dioxolane-4-methanol is known for its reactivity and versatility in chemical synthesis, making it a valuable intermediate in various chemical reactions.
Uses
Used in Chemical Synthesis:
2-Ethyl-1,3-dioxolane-4-methanol is used as a reagent in the selective ruthenium-mediated synthesis of mixed acetals and orthoesters. Its application is particularly relevant in the addition of alcohol and phenols to allyl ethers, where it serves as a key intermediate in the formation of these complex organic compounds. This reactivity and selectivity make it a valuable tool in the synthesis of a wide range of chemical products, including pharmaceuticals, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 53951-44-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,5 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 53951-44:
(7*5)+(6*3)+(5*9)+(4*5)+(3*1)+(2*4)+(1*4)=133
133 % 10 = 3
So 53951-44-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H12O3/c1-2-6-8-4-5(3-7)9-6/h5-7H,2-4H2,1H3
53951-44-3Relevant articles and documents
Synthesis of dioxolanylmethyl methacrylates from aldehydes, glycerol, and methyl methacrylate
Shevchuk,Podgornova,Yablonskii
, p. 522 - 523 (2001)
The feasibility of preparing dioxolanylmethyl methacrylates from aldehydes in two stages (without purification of intermediate 4-hydroxymethyl-1,3-dioxane) was examined.
A selective and convenient ruthenium mediated method for the synthesis of mixed acetals and orthoesters
Krompiec, Stanis?aw,Penczek, Robert,Ku?nik, Nikodem,Ma?ecki, Jan Grzegorz,Matlengiewicz, Marek
, p. 137 - 140 (2007/10/03)
Addition of alcohols and phenols to O-allyl compounds (allyl ethers and acrolein acetals), catalyzed by [RuCl2(PPh3)3], was examined. Intramolecular addition of an OH group, leading to the formation of cyclic acetals and o
Features of synthesis of 4-hydroxymethyl-1,3-dioxolanes from glycerol and aldehydes
Shevchuk,Podgornova,Piskaikina
, p. 853 - 856 (2007/10/03)
Specific features of reaction of glycerol with aldehydes, compared to ketones, were revealed, and formation of 4-hydroxymethyl-1,3-dioxolanes from glycerol and lower aldehydes (acetaldehyde, propionaldehyde, and butyraldehyde) was examined. The products were isolated, and their physicochemical characteristics were determined.
