54118-75-1

Basic information

• Product Name: 4-BROMO-4'-METHOXYBENZOPHENONE
• Synonyms: CHEMBRDG-BB 5314129;(4-BROMO-PHENYL)-(4-METHOXY-PHENYL)-METHANONE;4-BROMO-4'-METHOXYBENZOPHENONE
• CAS NO: 54118-75-1
• Molecular Formula: C₁₄H₁₁BrO₂
• Molecular Weight: 291.14
• Mol File: 54118-75-1.mol
• Article Data: 44

Chemical Properties

• Melting Point: 160-161 °C
• Boiling Point: 393.4 °C at 760 mmHg
• Flash Point: 191.7 °C
• Appearance: /
• Density: 1.401 g/cm³
• Vapor Pressure: 2.14E-06mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 4-BROMO-4'-METHOXYBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-4'-METHOXYBENZOPHENONE(54118-75-1)
• EPA Substance Registry System: 4-BROMO-4'-METHOXYBENZOPHENONE(54118-75-1)

Safety Data

• Hazardous Substances Data: 54118-75-1(Hazardous Substances Data)

Usage

General Description

4-Bromo-4'-methoxybenzophenone, also known as 4-(4-Bromophenyl)-4-methoxybenzophenone, is a chemical compound that belongs to the class of benzophenones. It is a white to off-white crystalline solid with a molecular formula of C14H11BrO2. 4-BROMO-4'-METHOXYBENZOPHENONE is used as a photoinitiator in the production of inks, adhesives, and coatings, where it initiates chemical reactions when exposed to ultraviolet or visible light. It is a versatile compound with applications in the fields of polymer chemistry, materials science, and pharmaceuticals. Additionally, it is utilized as an intermediate in the synthesis of various other organic compounds. However, it is important to handle 4-Bromo-4'-methoxybenzophenone with care, as it may be harmful if ingested or inhaled, and can cause irritation to the skin and eyes.

InChI:InChI=1/C14H11BrO2/c1-17-13-8-4-11(5-9-13)14(16)10-2-6-12(15)7-3-10/h2-9H,1H3

Upstream product

• 586-76-5 4-Bromobenzoic acid 
• 100-66-3 methoxybenzene 
• 586-75-4 4-chlorobenzoyl chloride 
• 59383-65-2 4-bromo(thiobenzoic) acid S-(4-chlorophenyl) ester 
• 33397-21-6 tris(4-methoxyphenyl)bismuth 
• 623-00-7 4-bromobenzenecarbonitrile 
• 6462-50-6 sodium 4-methoxybenzenesulfinate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 192436-83-2 4-bromo-N-methoxy-N-methylbenzamide 
• 1122-91-4 4-bromo-benzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 838-21-1 (4-bromophenyl)(4-methoxyphenyl)methanol 
• 53039-48-8 1-(4-bromobenzyl)-4-methoxybenzene 
• 5467-74-3 4-Bromophenylboronic acid 

Downstream Products

• 4369-50-0 4-hydroxyphenyl-(4-bromo-phenyl)-methanone 
• 1445534-88-2 C₁₅H₁₄BrNO₂ 
• 1428526-13-9 4-((4-hydroxy-2-(pyridin-2-yl)pyrimidine-5-carboxamido)(4-methoxyphenyl)methyl)phenylphosphonic acid 
• 1436432-74-4 N-Boc-(4-bromophenyl)(4-methoxyphenyl)methylamine 
• 886362-84-1 (4-bromophenyl)(4-methoxyphenyl)methanamine 
• 1428526-11-7 diethyl 4-(amino(4-methoxyphenyl)methyl)phenylphosphonate 
• 1428526-12-8 diethyl 4-((4-hydroxy-2-(pyridin-2-yl)pyrimidine-5-carboxamido)(4-methoxyphenyl)methyl)phenylphosphonate 
• 75607-30-6 (4-Bromo-phenyl)-(4-dimethylamino-phenyl)-(4-methoxy-phenyl)-methanol 

Relevant articles and documents

Thiophenol detection using an AIE fluorescent probe through self-assembly with TPE-based glycoclusters

We describe a novel green-emitting tetraphenylethylene-dicyanomethylene-4H-pyran (TPE-DCM) based fluorescent probe (TD-1). Conjugating TPE and DCM moieties allowed TD-1 to display high selectivity for thiophenol with excellent AIE properties in aqueous so

Discovery of Salidroside-Derivated Glycoside Analogues as Novel Angiogenesis Agents to Treat Diabetic Hind Limb Ischemia

Therapeutic angiogenesis is a potential therapeutic strategy for hind limb ischemia (HLI); however, currently, there are no small-molecule drugs capable of inducing it at the clinical level. Activating the hypoxia-inducible factor-1 (HIF-1) pathway in skeletal muscle induces the secretion of angiogenic factors and thus is an attractive therapeutic angiogenesis strategy. Using salidroside, a natural glycosidic compound as a lead, we performed a structure-activity relationship (SAR) study for developing a more effective and druggable angiogenesis agent. We found a novel glycoside scaffold compound (C-30) with better efficacy than salidroside in enhancing the accumulation of the HIF-1α protein and stimulating the paracrine functions of skeletal muscle cells. This in turn significantly increased the angiogenic potential of vascular endothelial and smooth muscle cells and, subsequently, induced the formation of mature, functional blood vessels in diabetic and nondiabetic HLI mice. Together, this study offers a novel, promising small-molecule-based therapeutic strategy for treating HLI.

AIBN initiated functionalization of the benzylic sp3 C[sbnd]H and C[sbnd]C bonds in the presence of dioxygen

A sp3 C[sbnd]H bond functionalization and C[sbnd]C bond cleavage were realized by AIBN/O2 catalyst system, providing a series of benzophenones under mild reaction conditions. The mechanistic study shows that a peroxide intermediate is involved in this transformation, and in the case of diphenylmethanes, the sp3 C[sbnd]C bond is cleaved through the peroxide rearrangement, which might provides a new way to cleave relatively strong C[sbnd]C bond and be applied to more general C[sbnd]C bond activation.