54278-10-3 Usage
Description
Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate is an organic compound characterized by its white or white crystalline appearance. It is a derivative of pyrrole, a heterocyclic compound with a five-membered ring containing two carbon atoms and two nitrogen atoms. This specific compound features a unique structure with a carboxylic ester group and two methyl groups at the 2nd and 4th positions, making it a valuable compound for various applications in chemical synthesis.
Uses
Used in Chemical Synthesis Studies:
Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a versatile building block for the development of new molecules with potential applications in pharmaceuticals, agrochemicals, and other industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate is used as a starting material for the synthesis of novel drug candidates. Its structural diversity and reactivity enable the creation of new molecules with potential therapeutic properties, contributing to the discovery of innovative treatments for various diseases and conditions.
Used in Agrochemical Industry:
Ethyl 2,4-dimethyl-5-(ethoxycarbonyl)-3-pyrrolepropionate is also utilized in the agrochemical industry for the development of new pesticides and other crop protection agents. Its unique chemical properties make it a valuable component in the design and synthesis of molecules with improved efficacy, selectivity, and environmental compatibility.
Check Digit Verification of cas no
The CAS Registry Mumber 54278-10-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,2,7 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 54278-10:
(7*5)+(6*4)+(5*2)+(4*7)+(3*8)+(2*1)+(1*0)=123
123 % 10 = 3
So 54278-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H21NO4/c1-5-18-12(16)8-7-11-9(3)13(15-10(11)4)14(17)19-6-2/h15H,5-8H2,1-4H3
54278-10-3Relevant articles and documents
(m.n)-Homorubins: Syntheses and structures
Pfeiffer, William P.,Lightner, David A.
, p. 1777 - 1801 (2015/02/19)
Five new homorubin analogs of bilirubin with their two dipyrrinone components conjoined to (CH2)2, (CH2)3, and (CH2)4 units were synthesized with propionic acid chains shortened to acetic and elongated to butyric, and examined by spectroscopy and molecular mechanics computations for an ability to form conformation-determining hydrogen bonds. With m designating the number of conjoining CH2 units and n indicating the number of CH2 units of the alkanoic acid chains of ( m.n)-homorubins, (2.1)-, (3.2)-, (4.2)-, and (4.3)-homorubins were prepared and compared with previously synthesized (2.2) and (2.3), which adopt intramolecularly hydrogen-bonded conformations in CHCl3.
FORMULATIONS FOR PHARMACEUTICAL AGENTS IONIZABLE AS FREE ACIDS OR FREE BASES
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Page/Page column 211, (2008/06/13)
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SYNTHESIS AND UNUSUAL PROPERTIES OF C(10)-gem-DIMETHYL BILIRUBIN ANALOGS
Xie, Meiqiang,Lightner, David A.
, p. 2185 - 2200 (2007/10/02)
The characteristic thermodynamically-favored intramolecularly hydrogen-bonded conformation adopted by bilirubin pigments is destabilized by substituting methyl groups on the C(10) central methylene.These methyl groups impose conformation-destabilizing methyl-methylene non-bonded steric interactions with the propionic acid β-CH2 groups at C(8) and C(12) when the propionic acids are engaged in intramolecular hydrogen bonding with the opposing dipyrrinones.Amphiphilic 10,10-dimethylbilirubins (1) and (2) are found to be more polar, but also more soluble than the parents (3) and (4) in organic solvents; yet, 1H-NMR studies in non-polar solvents indicate that a deformed but folded, intramolecularly hydrogen-bonded conformation is retained.The dimethyl esters of 10,10-dimethylbilirubins 1 and 2 did not exhibit the typical strong tendency of bilirubin dimethyl esters to form intermolecular hydrogen bonds in non-polar solvents such as chloroform and benzene.
