55860-35-0

Basic information

• Product Name: 4-acetyl-2-methyl benzoic acid
• Synonyms: 4-acetyl-2-methyl benzoic acid
• CAS NO: 55860-35-0
• Molecular Weight: 178.188
• Mol File: 55860-35-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 352.7±30.0 °C(Predicted)
• Density: 1.189±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-acetyl-2-methyl benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetyl-2-methyl benzoic acid(55860-35-0)
• EPA Substance Registry System: 4-acetyl-2-methyl benzoic acid(55860-35-0)

Safety Data

• Hazardous Substances Data: 55860-35-0(Hazardous Substances Data)

Usage

Description

4-Acetyl-2-methyl benzoic acid, also known as 2-methyl-4-acetylbenzoic acid, is an organic compound with the molecular formula C9H8O3. It is a derivative of benzoic acid, featuring a methyl group at the 2nd position and an acetyl group at the 4th position. 4-acetyl-2-methyl benzoic acid is characterized by its potential applications in various chemical and pharmaceutical processes due to its unique structural properties.

Uses

Used in Organic Synthesis:
4-Acetyl-2-methyl benzoic acid is used as an organic synthesis intermediate for the production of various chemical compounds. Its versatile structure allows it to be a key component in the synthesis of a wide range of organic molecules, contributing to the development of new materials and substances.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-acetyl-2-methyl benzoic acid is utilized as a pharmaceutical intermediate. It plays a crucial role in the development of new drugs and medicines, particularly in the synthesis of active pharmaceutical ingredients (APIs) that target specific medical conditions.
Used in Laboratory Research and Development:
4-Acetyl-2-methyl benzoic acid is also employed in laboratory research and development processes. It serves as a valuable compound for scientists and researchers to study its properties, reactivity, and potential applications in various fields, including chemistry, biology, and materials science.
Used in Chemical Production Processes:
4-acetyl-2-methyl benzoic acid is further used in chemical production processes, where it can be transformed into other valuable chemicals or materials. Its involvement in these processes highlights the importance of 4-acetyl-2-methyl benzoic acid as a building block for the chemical industry.

Upstream product

• 1138444-80-0 3-methyl-4-cyanoacetophenone 
• 95-52-3 2-Fluorotoluene 
• 369-32-4 1-(4-fluoro-3-methylphenyl)ethanone 
• 3637-01-2 3,4-dimethylacetophenone 
• 111-34-2 -butyl vinyl ether 
• 68837-59-2 4-bromo-2-methylbenzoic acid 
• 201230-82-2 carbon monoxide 
• 37074-40-1 1-(4-bromo-3-methylphenyl)ethan-1-one 
• 1530-36-5 [(2-methylphenyl)methyl]triphenylphosphonium bromide 
• 57542-70-8 α,α'-dibromo-2,2'-dimethyl-bibenzyl 
• 5294-03-1 di-o-tolylethyne 
• 10311-74-7 2,2'-dimethyl-stilbene 

Downstream Products

• 1095275-09-4 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid diethylamine salt 
• 1095275-08-3 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoate triethylamine 
• 1095275-07-2 4-(3-(3,5-dichlorophenyl)-4,4,4-trifluoro-3-hydroxybutanoyl)-2-methylbenzoic acid 
• 1095275-05-0 4-acetyl-2-methyl benzoyl chloride 
• 1309959-52-1 4-acetyl-N-[(4R)-2-ethyl-3-oxo-isoxazolidin-4-yl]-2-methyl-benzamide 
• 1332628-87-1 4-acetyl-2-methyl-N-thietan-3-ylbenzamide 
• 1332628-88-2 4-[(E)-3-(3,5-dichloro-phenyl)-4,4,4-trifluoro-but-2-enoyl]-2-methyl-N-thietan-3-yl-benzamide 
• 1332628-94-0 4-acetyl-2-methyl-N-(1,1-dioxidethietan-3-yl)benzamide 
• 1332628-95-1 4-[(E)-3-(3,5-dichlorophenyl)-4,4,4-trifluorobut-2-enoyl]-2-methyl-N-(1,1-dioxidethietan-3-yl)benzamide 
• 864731-61-3 A₁₄₄₃ 
• 1391709-90-2 4-(5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-89-9 4-(5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-88-8 4-(4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl)-2-methylbenzohydrazide 
• 1391709-87-7 4-(4,5-dihydro-5-phenyl-1H-pyrazol-3-yl)-2-methylbenzohydrazide 

Relevant articles and documents

Method for synthesizing methyl 2-methyl-4-acetyl benzoate

The invention provides a method for synthesizing methyl 2-methyl-4-acetyl benzoate. The method comprises the following steps: (1) adding an acylating reagent to a solution with dissolved 2-fluorotoluene, and carrying out an acylation reaction so as to obtain 4-fluoro-3-methylacetophenone; (2) dissolving the obtained 4-fluoro-3-methylacetophenone, adding a cyanation reagent, and carrying out a cyanation reaction so as to obtain 3-methyl-4-cyanoacetophenone; (3) adding acid to the 3-methyl-4-cyanoacetophenone, and carrying out a hydrolysis reaction so as to obtain 2-methyl-4-acetylbenzoic acid;and (4) adding methanol to the 2-methyl-4-acetylbenzoic acid, and carrying out an esterification reaction so as to obtain methyl 2-methyl-4-acetyl benzoate. The method has simple operation, a high reaction yield, easily purchasable reagents and instruments and low cost, and is feasible in specific practical application.

METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND, METHOD FOR PRODUCTION OF 2-PROPEN-1-ONE COMPOUND, AND METHOD FOR PRODUCTION OF ISOXAZOLINE COMPOUND

There is provided a novel intermediate for producing pesticides. A method for producing 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4) and a substituted acetophenone compound of Formula (5) as starting raw materials in an organic solvent or water in the presence or absence of an additive in the presence of a base in a suspended state. A method for producing 1,3-bis(substituted phenyl)-3-substituted-2-propen-2-one compound of Formula (2) comprises dehydrating the compound of Formula (3). A method for producing compound (2) in one step comprises reacting compound (4) and compound (5) to obtain compound (3). Further, a method for producing an isoxazoline compound of Formula (1) comprises reacting compound (2) and a hydroxylamine in an aliphatic or an aromatic hydrocarbon solvent which is optionally substituted by a halogen atom by adding an additive selected from a phase-transfer catalyst, a C1-C6 alcohol and an aprotic polar solvent in the presence of a base and water.