56891-59-9

Basic information

• Product Name: N1-(4-AMINO-2-METHYLPHENYL)ACETAMIDE
• Synonyms: N1-(4-AMINO-2-METHYLPHENYL)ACETAMIDE;N-(4-AMINO-2-METHYL-PHENYL)-ACETAMIDE;N1-(4-Amino-2-methylphenyl)acetamide, tech;4-Acetylamino-m-toluidine;4'-Amino-2'-methylacetanilide;N-(4-Amino-2-methylphenyl)acetamide, 4-Acetamido-3-methylaniline
• CAS NO: 56891-59-9
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.2
• Mol File: 56891-59-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 141 °C
• Boiling Point: 259.9°Cat760mmHg
• Flash Point: 111°C
• Appearance: /
• Density: 1.163g/cm³
• Vapor Pressure: 0.0126mmHg at 25°C
• Refractive Index: 1.62
• Storage Temp.: 2-8°C(protect from light)
• PKA: 14.76±0.70(Predicted)
• CAS DataBase Reference: N1-(4-AMINO-2-METHYLPHENYL)ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(4-AMINO-2-METHYLPHENYL)ACETAMIDE(56891-59-9)
• EPA Substance Registry System: N1-(4-AMINO-2-METHYLPHENYL)ACETAMIDE(56891-59-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 56891-59-9(Hazardous Substances Data)

Usage

General Description

N1-(4-Amino-2-methylphenyl)acetamide is a chemical compound with the molecular formula C9H12N2O. It is an amide derivative of 4-amino-2-methylphenol, commonly known as paracetamol or acetaminophen. The compound is commonly used as an intermediate in the synthesis of pharmaceuticals and can also serve as a building block for the preparation of various organic compounds. It has potential applications in the field of medicinal chemistry for the development of new drugs. The compound’s chemical structure and properties make it suitable for use in the pharmaceutical industry and for research purposes.

InChI:InChI=1/C9H12N2O/c1-6-5-8(10)3-4-9(6)11-7(2)12/h3-5H,10H2,1-2H3,(H,11,12)

Upstream product

• 108-24-7 acetic anhydride 
• 95-70-5 2-methyl-p-phenylenediamine 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 2719-15-5 2-methyl-4-nitroacetanilide 

Downstream Products

• 63233-38-5 2-acetylamino-5-(toluene-4-sulfonylamino)-toluene 
• 873402-91-6 toluene-4-sulfonic acid-(4-amino-3-methyl-anilide) 
• 56891-60-2 4-acetamino-3-methyl-N-ethylaniline 
• 87223-52-7 C₁₄H₁₈N₄O₅ 
• 105168-57-8 C₁₁H₁₇N₃O₃S 
• 105168-63-6 N-[2-Methyl-4-(morpholine-4-sulfonylamino)-phenyl]-acetamide 
• 105168-60-3 N-[2-Methyl-4-(piperidine-1-sulfonylamino)-phenyl]-acetamide 
• 93-37-8 2,7-dimethylquinoline 
• 105168-65-8 C₁₆H₂₃N₅O₇S 
• 105168-62-5 C₁₇H₂₅N₅O₆S 
• 105168-59-0 C₁₄H₂₁N₅O₆S 
• 105168-64-7 Morpholine-4-sulfonic acid (4-amino-3-methyl-phenyl)-amide 
• 105168-61-4 Piperidine-1-sulfonic acid (4-amino-3-methyl-phenyl)-amide 
• 105168-58-9 C₉H₁₅N₃O₂S 

Relevant articles and documents

NOVEL IMIDAZO-PYRAZINE DERIVATIVES

The invention provides novel imidazo-pyrazine derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, m, n, and R1to R3 are as described herein: formula (I). Further provided are pharmace

Quinone Imine Route to Benzimidazol-2-ylcarbamates. Part 1. Synthesis of Open-chain and Cyclic 5-Acylamino Derivatives.

The synthesis of the N',N''-bismethoxycarbonyl-N-(4-acylaminophenyl)guanidines (4) and (7) is described.Oxidation of these with LTA has led to the benzimidazol-2-ylcarbamates. (8), (9) and (10) through a regiospecific cyclisation of quinone imine intermediates.If the acylamino group is part of a ring, the yield of benzimidazoles (15) increases with the size of the lactam ring.The direction of ring closure may be controlled by electronic and steric factors.