569354-60-5

Basic information

• Product Name: Benzamide, 2-(aminomethyl)-5-fluoro-N-methyl-, monohydrochloride
• CAS NO: 569354-60-5
• Molecular Formula: C9H11FN2O.ClH
• Mol File: 569354-60-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-(aminomethyl)-5-fluoro-N-methyl-, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-(aminomethyl)-5-fluoro-N-methyl-, monohydrochloride(569354-60-5)
• EPA Substance Registry System: Benzamide, 2-(aminomethyl)-5-fluoro-N-methyl-, monohydrochloride(569354-60-5)

Safety Data

• Hazardous Substances Data: 569354-60-5(Hazardous Substances Data)

Upstream product

• 70931-59-8 1-(bromomethyl)-4-fluoro-2-iodobenzene 
• 13194-67-7 4-fluoro-2-iodotoluene 
• 606138-71-0 C₁₇H₂₃FINO₄ 
• 201230-82-2 carbon monoxide 
• 74-89-5 methylamine 
• 569354-59-2 N-methyl 2-t-butyloxycarbonylaminomethyl-5-fluorobenzenecarboxamide 
• 138786-65-9 methyl 2-(bromomethyl)-5-fluorobenzoate 
• 175278-29-2 5-fluoro-2-methylbenzoic acid methyl ester 
• 569354-58-1 C₁₉H₂₆FNO₆ 

Relevant articles and documents

A potent and orally active HIV-1 integrase inhibitor

A 1,6-naphthyridine inhibitor of HIV-1 integrase has been discovered with excellent inhibitory activity in cells, good pharmacokinetics, and an excellent ability to inhibit virus with mutant enzyme.

Preparation of 2-aminomethyl-5-fluorobenzamides

Benzamide compounds of Formula VII are prepared by reacting a benzoate compound of Formula V with an amine to obtain a benzamide compound of Formula VI, and then treating the benzamide VI with an amine deprotecting agent to obtain the benzamide VII; where