581812-91-1

Basic information

• Product Name: (S)-N-[α-methyl-4-(trifluoromethyl)benzyl] (R)-2-acetoxy-2-phenylethanamide
• Synonyms: (S)-N-[α-methyl-4-(trifluoromethyl)benzyl] (R)-2-acetoxy-2-phenylethanamide
• CAS NO: 581812-91-1
• Molecular Weight: 365.352
• Mol File: 581812-91-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-N-[α-methyl-4-(trifluoromethyl)benzyl] (R)-2-acetoxy-2-phenylethanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-[α-methyl-4-(trifluoromethyl)benzyl] (R)-2-acetoxy-2-phenylethanamide(581812-91-1)
• EPA Substance Registry System: (S)-N-[α-methyl-4-(trifluoromethyl)benzyl] (R)-2-acetoxy-2-phenylethanamide(581812-91-1)

Safety Data

• Hazardous Substances Data: 581812-91-1(Hazardous Substances Data)

Upstream product

• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 51019-43-3 (R)-(-)-O-acetylmandelic acid 
• 15996-84-6 1-(4-trifluoromethylphenyl)ethylamine 
• 107496-43-5 1-(4-(trifluoromethyl)phenyl)ethan-1-one O-methyl oxime 

Downstream Products

• 84499-73-0 (S)-N-[α-ethyl-4-(trifluoromethyl)benzyl]amine 

Relevant articles and documents

Trading N and O. Part 3: Synthesis of 1,2,3,4-tetrahydroisoquinolines from α-hydroxy-β-amino esters

A range of enantiopure 1,2,3,4-tetrahydroisoquinolines have been prepared directly from α-hydroxy-β-amino esters. Activation of the α-hydroxy group upon treatment with Tf2O and 2,6-di-tert-butyl-4-methylpyridine promotes aziridinium formation,

Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor

Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity.