6069-36-9Relevant articles and documents
1,3-Dimethyl-2-(3-nitro-1,2,4-triazol-1-yl)-2-pyrrolidin-1-yl-1,3, 2-diazaphospholidinium hexafluorophosphate (MNTP): A powerful condensing reagent for phosphate and phosphonate esters
Oka, Natsuhisa,Shimizu, Mamoru,Saigo, Kazuhiko,Wada, Takeshi
, p. 3667 - 3673 (2006)
A novel phosphonium-type condensing reagent, 1,3-dimethyl-2-(3-nitro-1,2,4- triazol-1-yl)-2-pyrrolidin-1-yl-1,3,2-diazaphospholidinium hexafluorophosphate (MNTP), was designed and synthesized. A 31P NMR study on the condensation reactions of ph
The synthesis of novel phospholipids related to ethylenediamine
Anson,McGuigan
, p. 1275 - 1276 (1987)
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Total synthesis of alkaloid 205B
Tsukanov, Sergey V.,Comins, Daniel L.
supporting information, p. 9074 - 9085 (2015/02/19)
Concise and highly stereocontrolled total syntheses of racemic and enantiopure frog alkaloid 205B (1) were accomplished in 11 steps from 4-methoxypyridines 6 and 7 in overall yields of 8 and 8%, respectively. The assembly of the core of the natural product relies on a stereoselective Tsuji-Trost allylic amination reaction and a ring-closing metathesis. The synthesis features the use of an N-acylpyridinium salt reaction to introduce the first stereocenter and an unprecedented trifluoroacetic anhydride-mediated addition of an allylstannane to a vinylogous amide with complete facial selectivity. Deoxygenation of the C4 ketone proved difficult but was accomplished via a modified Barton-McCombie reaction in the presence of a catalytic amount of diphenyl diselenide.
A divergent synthesis of minor groove binders with tail group variation
Breen, David,Kennedy, Alan R.,Suckling, Colin J.
experimental part, p. 178 - 186 (2009/04/07)
A new synthesis of polyamide minor groove binders in which diversity is introduced by the nucleophilic substitution of a 2-sulfido-1,3,2- diazaphospholidinyloxy substituent by volatile secondary amine nucleophiles is described. Such a method has potential