6230-73-5

Basic information

• Product Name: 2-Propen-1-one, 1-(4-chlorophenyl)-2-methyl-
• CAS NO: 6230-73-5
• Molecular Formula: C10H9ClO
• Molecular Weight: 180.634
• Mol File: 6230-73-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(4-chlorophenyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(4-chlorophenyl)-2-methyl-(6230-73-5)
• EPA Substance Registry System: 2-Propen-1-one, 1-(4-chlorophenyl)-2-methyl-(6230-73-5)

Safety Data

• Hazardous Substances Data: 6230-73-5(Hazardous Substances Data)

Upstream product

• 67-64-1 acetone 
• 39184-66-2 (4-chlorophenyl)chlorodiazirine 
• 124-38-9 carbon dioxide 
• 1450-09-5 (α-4-chlorobenzoylethylidene)triphenylphosphorane 
• 122-01-0 4-chloro-benzoyl chloride 
• 557-93-7 2-bromoprop-1-ene 
• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 6285-05-8 4'-chloropropiophenone 
• 67-68-5 dimethyl sulfoxide 
• 13856-85-4 1-(4-chlorophenyl)-1-propanol 
• 106-39-8 bromochlorobenzene 
• 100-97-0 hexamethylenetetramine 
• 104-88-1 4-chlorobenzaldehyde 
• 911850-35-6 1-(4-chlorophenyl)-2-methylprop-2-en-1-ol 

Downstream Products

• 99234-44-3 (4-Chloro-phenyl)-(2-methoxy-1-methyl-4-trimethylsilanyloxy-cyclohex-3-enyl)-methanone 
• 116981-05-6 [(Z)-1-(4-Chloro-phenyl)-3-iodo-2-methyl-propenyloxy]-trimethyl-silane 
• 92748-94-2 5-(4-Chloro-phenyl)-2,6-dimethyl-6,7-dihydro-[1,3,4]oxadiazepine 
• 116981-10-3 [2,6-Bis-(4-chloro-phenyl)-3-iodomethyl-3,5-dimethyl-3,4-dihydro-2H-pyran-2-yloxy]-trimethyl-silane 
• 99221-29-1 4-(4-chlorobenzoyl)-4-methylcyclohexa-2,5-dienone 
• 99221-36-0 4-(4-chlorobenzoyl)-4-methylcyclohex-2-enone 
• 99234-41-0 1-trimethylsilyloxy-4-(4-chlorobenzoyl)-4-methylcyclohexa-1,5-diene 
• 1140916-77-3 (4-chlorophenyl)-[2-(4-fluorophenylthio)-1-methylethyl]ketone 
• 18713-58-1 1-(4-chlorophenyl)-2-methylpropan-1-one 
• 911850-35-6 1-(4-chlorophenyl)-2-methylprop-2-en-1-ol 

Relevant articles and documents

Br?nsted Base-Catalyzed Transformation of α,β-Epoxyketones Utilizing [1,2]-Phospha-Brook Rearrangement for the Synthesis of Allylic Alcohols Having a Tetrasubstituted Alkene Moiety

A stereoselective transformation of α,β-epoxyketones into alkenylphosphates having a hydroxymethyl group on the β-carbon was established by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. The reaction involves the catalytic generation of an α-oxygenated carbanion located at the α-position of an epoxide moiety through the [1,2]-phospha-Brook rearrangement and the following epoxide opening. Further transformation of the alkenylphosphates by the palladium-catalyzed cross-coupling reaction with Grignard reagents provided allylic alcohols having a stereodefined all-carbon tetrasubstituted alkene moiety.

Method for synthesizing alpha,beta-unsaturated ketone compounds from dimethyl sulfoxide and ketone compounds

The invention discloses a method for synthesizing alpha,beta-unsaturated ketone compounds from dimethyl sulfoxide and ketone compounds. According to the method, dimethyl sulfoxide and ketone compoundsare subjected to a one-pot reaction in the presence of carboxylate and persulfate so as to produce the alpha,beta-unsaturated ketone compounds. The method uses dimethyl sulfoxide as a methylenation reagent and employs a one-pot process for high-selectivity high-yield synthesis of the alpha,beta-unsaturated ketone compounds from the ketone compounds; and the method is simple to operate, low in cost, friendly to environment and beneficial for industrial production.

A methylene compound of preparation method and its application (by machine translation)

The invention discloses a methylene compound of preparation method and its application, relates to the field of organic synthesis, the process comprises: 1) in the presence of a three-valent metal salt catalyst, will arone compound and halogen methyl radical trialkyl ammonium salt dissolved in a solvent, 2) 80 - 130 °C reaction 1 - 4 hours, separated and purified α - the methyl radical is fragrant compounds, the reaction environment pollution is small, substrate and wide range of application. (by machine translation)