624-96-4 Usage
Description
1,3-Dichloro-3-methylbutane, also known as 1,3-DCMB, is an organic compound with the chemical formula C5H10Cl2. It is a colorless liquid with a chlorinated hydrocarbon structure, featuring two chlorine atoms and a methyl group attached to a butane chain. 1,3-DICHLORO-3-METHYLBUTANE is known for its reactivity and is commonly utilized in various chemical synthesis processes.
Uses
1,3-Dichloro-3-methylbutane is used as a reagent in the synthesis of Precocene analogs, which exhibit anti-juvenile hormone activity against Oxycarenus lavaterae. 1,3-DICHLORO-3-METHYLBUTANE plays a crucial role in the development of these analogs, which have potential applications in pest control and understanding the hormonal regulation of insect development.
Used in Chemical Synthesis:
1,3-Dichloro-3-methylbutane is used as a versatile reagent for the synthesis of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, such as substitution, addition, and elimination reactions, making it a valuable building block in the creation of complex molecules.
Used in Pest Control Research:
1,3-Dichloro-3-methylbutane is used as a key intermediate in the development of Precocene analogs, which have shown potential as pest control agents. By disrupting the juvenile hormone activity in insects, these analogs can effectively control pest populations, offering an alternative to traditional chemical pesticides.
Used in Pharmaceutical Research:
The synthesis of Precocene analogs using 1,3-dichloro-3-methylbutane also has implications in the pharmaceutical industry. These analogs may provide insights into the hormonal regulation of insect development, which could lead to the development of new drugs targeting specific hormonal pathways in humans.
Check Digit Verification of cas no
The CAS Registry Mumber 624-96-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 624-96:
(5*6)+(4*2)+(3*4)+(2*9)+(1*6)=74
74 % 10 = 4
So 624-96-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H10Cl2/c1-5(2,7)3-4-6/h3-4H2,1-2H3
624-96-4Relevant articles and documents
Stammann,Griesbaum
, p. 1705 (1979)
Formamides as Lewis Base Catalysts in SNReactions—Efficient Transformation of Alcohols into Chlorides, Amines, and Ethers
Huy, Peter H.,Motsch, Sebastian,Kappler, Sarah M.
supporting information, p. 10145 - 10149 (2016/08/16)
A simple formamide catalyst facilitates the efficient transformation of alcohols into alkyl chlorides with benzoyl chloride as the sole reagent. These nucleophilic substitutions proceed through iminium-activated alcohols as intermediates. The novel method, which can be even performed under solvent-free conditions, is distinguished by an excellent functional group tolerance, scalability (>100 g) and waste-balance (E-factor down to 2). Chiral substrates are converted with excellent levels of stereochemical inversion (99 %→≥95 % ee). In a practical one-pot procedure, the primary formed chlorides can be further transformed into amines, azides, ethers, sulfides, and nitriles. The value of the method was demonstrated in straightforward syntheses of the drugs rac-Clopidogrel and S-Fendiline.
