626-29-9 Usage
Description
Myristic anhydride is an anhydride of myristic acid, a naturally occurring fatty acid. It is a key intermediate in the synthesis of various fatty acyl derivatives and macrocyclic peptides, playing a significant role in the chemical and pharmaceutical industries.
Uses
Used in Chemical Synthesis:
Myristic anhydride is used as a reactant for the synthesis of cholesteryl myristate by reacting with cholesterol. This application is crucial in the production of certain pharmaceutical compounds and substances with specific biological activities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, myristic anhydride is used as a reactant in the synthesis of 1,2-dimyristoyl-sn-glycero-3-phosphocholine by acylating sn-glycero-3-phosphocholine. MYRISTIC ANHYDRIDE has potential applications in drug development and delivery systems.
Used in Cationic Lipid Synthesis:
Myristic anhydride serves as a reagent in the synthesis of 3-(bis-2-(tert-butyldimethylsilyloxy)ethylamino)propane-1,2-diol, an intermediate of cationic lipid. Cationic lipids are essential components in the formulation of gene delivery systems, such as liposomes, which are used in gene therapy and other medical applications.
Used in Fragrance Industry:
As a reactant, myristic anhydride is used to synthesize neryl myristate by reacting with nerol. Neryl myristate is a valuable component in the fragrance industry, adding unique scents to various products.
Used in Peptide Synthesis:
Myristic anhydride is also used as a reagent to synthesize myristoylated t-butylglutamic acid by myristoylation of γ-tert-butoxy-glutamic acid. This process is essential in the development of macrocyclic peptides, which have potential applications in various fields, including pharmaceuticals and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 626-29-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 626-29:
(5*6)+(4*2)+(3*6)+(2*2)+(1*9)=69
69 % 10 = 9
So 626-29-9 is a valid CAS Registry Number.
InChI:InChI=1/C28H54O3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27(29)31-28(30)26-24-22-20-18-16-14-12-10-8-6-4-2/h3-26H2,1-2H3
626-29-9Relevant articles and documents
Use of glycerol carbonate in an efficient, one-pot and solvent free synthesis of 1,3-sn-diglycerides
Kargar, Mojgan,Hekmatshoar, Rahim,Ghandi, Mehdi,Mostashari, Abdoljalil
, p. 259 - 264 (2013/07/27)
An efficient solvent-free synthesis of a variety of highly pure 1,3-sn-diglycerides (1,3-sn-diacylglycerols) in a two-step one pot process is described. Heating glycerol carbonate (4-hydroxymethyl-1,3-dioxolan-2-one) with fatty acid anhydrides 2a-d affords 1:1 mixtures of glycerol carbonate fatty esters 3a-3d and the corresponding fatty acids. Further heating the reaction mixtures in the presence of catalytic amounts of 1,4-diazabicyclo[2.2.2]octane (DABCO) at 195-200 °C yields highly pure 1,3-sn-diglycerides 4a-4d.
A NEW SYNTHESIS OF CARBOXYLIC AND CARBONIC ACID ANHYDRIDES USING PHASE TRANSFER REACTIONS
Plusquellec, Daniel,Roulleau, Fabienne,Lefeuvre, Martine,Brown, Eric
, p. 2471 - 2476 (2007/10/02)
Acyl chlorides and alkylchloroformates smoothly reacted with one molar equivalent of sodium hydroxide, using liquid-liquid phase transfer conditions to afford high yields of the corresponding symmetrical carboxylic and carbonic hemiester anhydrides.Unstable anhydrides such as 4-nitrobenzoic, 2-furoic and methacrylic anhydrides, which are otherwise difficult to obtain, were easily prepared by this method.The reaction mechanism does not seem to involve intermediate hydrolysis of half the acid chloride into the corresponding sodium carboxylate.
