6325-41-3

Basic information

• Product Name: 3-Methyl-3-phenyl-butanal
• Synonyms: 3-Methyl-3-phenyl-butanal
• CAS NO: 6325-41-3
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.22826
• Mol File: 6325-41-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 227°Cat760mmHg
• Flash Point: 94.5°C
• Appearance: /
• Density: 0.954g/cm³
• Vapor Pressure: 0.0794mmHg at 25°C
• Refractive Index: 1.493
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-Methyl-3-phenyl-butanal(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-3-phenyl-butanal(6325-41-3)
• EPA Substance Registry System: 3-Methyl-3-phenyl-butanal(6325-41-3)

Safety Data

• Hazardous Substances Data: 6325-41-3(Hazardous Substances Data)

Usage

General Description

3-methyl-3-phenyl-butanal, also known as 3-methyl-3-phenylbutanal, is a chemical compound with the molecular formula C11H14O. It is a colorless to pale yellow liquid with a strong, sweet, floral odor. 3-methyl-3-phenyl-butanal is commonly used as a flavoring agent in the food industry, providing a fruity and floral aroma to various products. It is also used in the production of perfumes and fragrances due to its pleasant scent. 3-methyl-3-phenyl-butanal is a key ingredient in the creation of complex and nuanced scents, and it is valued for its ability to add depth and richness to fragrances. Additionally, it has been studied for its potential antimicrobial and antioxidant properties, making it a versatile and valuable chemical in various industrial applications.

InChI:InChI=1/C11H14O/c1-11(2,8-9-12)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3

Upstream product

• 67-66-3 chloroform 
• 35293-35-7 2-methyl-2-phenyl-1-propylmagnesium chloride 
• 122-51-0 orthoformic acid triethyl ester 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 515-40-2 neophyl chloride 
• 21438-74-4 3-methyl-3-phenylbutan-1-ol 
• 1010-48-6 3-methyl-3-phenylbutanoic acid 
• 3805-10-5 2,2-(dimethyl)-2-phenylacetaldehyde 
• 22881-48-7 2-phenylpropan-2-yl vinyl ether 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 66622-39-7 4-methyl-4-phenylpent-1ene 
• 2629-47-2 diphenylantimony(III) chloride 
• 556-82-1 3-methyl-2-buten-1-ol 

Downstream Products

• 253185-03-4 tert-butylbenzene 
• 538-93-2 1-phenyl-2-methylpropane 
• 4094-64-8 3-methyl-3-phenyl-butyryl chloride 
• 93137-16-7 3-methyl-3-phenyl-butyraldehyde-semicarbazone 
• 66622-39-7 4-methyl-4-phenylpent-1ene 
• 17684-33-2 β,β-dimethyl-β-phenylpropionitrile 
• 881392-78-5 2-amino-4-methyl-4-phenyl-pentanoic acid 
• 136281-92-0 3-(2-phenylpropan-2-yl)-1H-indole 
• 55106-22-4 Brom-2 methyl-3 phenyl-3 butanal 
• 28793-11-5 ((E)-1,1,6-Trimethyl-hepta-3,5-dienyl)-benzene 
• 67-66-3 chloroform 

Relevant articles and documents

Nickel-Catalyzed Selective Reduction of Carboxylic Acids to Aldehydes

The direct reduction of carboxylic acids to aldehydes is a fundamental transformation in organic synthesis. The combination of an air-stable Ni precatalyst, dimethyl dicarbonate as an activator, and silane reductant effects this reduction for a wide variety of substrates, including pharmaceutically relevant structures, in good yields and with no overreduction to alcohols. Moreover, this methodology is scalable, allows access to deuterated aldehydes, and is also compatible with one-pot utilization of the aldehyde products.

Synthesis of 2-tetralone derivatives by Bi(OTf)3-catalyzed intramolecular hydroarylation/isomerization of propargyl alcohols

Compared to 1-tetralones, 2-tetralones are expensive, less stable, and difficult to synthesize. A concise Bi-catalyzed method was developed for the synthesis of 2-tetralones from 5-phenylpent-1-yn-3-ol derivatives. Diverse 2-tetralones were obtained in moderate to good yields under mild conditions.

PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS

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