63703-34-4Relevant articles and documents
Morpholinosulfur trifluoride (morph-DAST)-mediated rearrangement in the fluorination of cyclic α,α-dialkoxy ketones toward 1,2-dialkoxy-1,2-difluorinated compounds
Surmont, Riccardo,Verniest, Guido,De Groot, Alex,Thuring, Jan Willem,De Kimpe, Norbert
scheme or table, p. 2751 - 2756 (2010/12/25)
The deoxofluorination of cyclic α,α-dialkoxy ketones with morpholinosulfur trifluoride (Morph-DAST) resulted in 1,2-dialkoxy-1,2- difluorinated carbo- and heterocyclic compounds. The reaction proceeds via a 1,2-alkoxy migration leading to mixtures of cis-
α-Hydroxylation of carbonyls using iodine
Zacuto, Michael J.,Cai, Dongwei
, p. 447 - 450 (2007/10/03)
The α-hydroxylation of ketones and aldehydes to α-hydroxyketals mediated by iodine under basic conditions in MeOH is described. Enolates generated under the reaction conditions are iodinated and the resulting α-iodocarbonyl is transformed into the hydroxyketal. The use of iodine for this chemistry represents an economical and practical alternative to existing methods for this transformation.
Indirect electrochemical oxidation of cyclic ketones: Influence of ring size, mediator and supporting electrolyte on the result of the reaction
Barba, Fructuoso,Elinson, Michail N.,Escudero, Jose,Feducovich, Sergey K.
, p. 4427 - 4436 (2007/10/03)
The result of the indirect electrochemical oxidation of cyclic ketones in methanol in an undivided cell in the presence of sodium halides depends on the ring size of ketone and the type of mediator. Selectivity of the reaction in some cases and current efficiency are increased by addition of supporting electrolyte - sodium hydroxide. Formation of cyclic 2,2-dimethoxycycloalkanols and the electrochemically induced Favorskii rearrangement with the formation of methyl cycloalkencarboxylates containing in the ring one carbon atom less than starting ketone are the main ways of the indirect electrochemical oxidation of cyclic ketones.