65227-53-4 Usage
Description
3-Pyridinesulfonic acid, hydrazide is a hydrazide derivative of pyridinesulfonic acid with the molecular formula C5H7N3O2S. It is a white to off-white powder that is soluble in water and is commonly used as a reagent in chemical reactions. This versatile compound has various industrial and research applications, making it a valuable building block in the synthesis of different compounds.
Uses
Used in Pharmaceutical Industry:
3-Pyridinesulfonic acid, hydrazide is used as a building block for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Pyridinesulfonic acid, hydrazide serves as a building block for the synthesis of various agrochemical compounds. Its use contributes to the development of new pesticides, herbicides, and other agricultural chemicals to improve crop protection and yield.
Used as a Reagent for Aldehyde and Ketone Determination:
3-Pyridinesulfonic acid, hydrazide is used as a reagent for the determination of aldehydes and ketones in chemical analysis. Its ability to react with these compounds makes it a valuable tool in identifying and quantifying their presence in various samples.
Used in Organic Synthesis:
3-Pyridinesulfonic acid, hydrazide has potential applications in the field of organic synthesis. Its unique chemical properties enable the synthesis of a wide range of organic compounds, contributing to the development of new materials and chemical processes.
Used in Material Science:
In material science, 3-Pyridinesulfonic acid, hydrazide can be utilized in the development of new materials with specific properties. Its versatility allows for its incorporation into various materials, potentially leading to advancements in areas such as polymers, catalysts, and sensors.
Check Digit Verification of cas no
The CAS Registry Mumber 65227-53-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,2,2 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65227-53:
(7*6)+(6*5)+(5*2)+(4*2)+(3*7)+(2*5)+(1*3)=124
124 % 10 = 4
So 65227-53-4 is a valid CAS Registry Number.
65227-53-4Relevant articles and documents
Synergy of anodic oxidation and cathodic reduction leads to electrochemical deoxygenative C2 arylation of quinoline: N-oxides
Yuan, Yong,Jiang, Minbao,Wang, Tao,Xiong, Yunkui,Li, Jun,Guo, Huijiao,Lei, Aiwen
supporting information, p. 11091 - 11094 (2019/09/20)
The first example of electrochemical deoxygenative C2 arylation of quinoline N-oxides using sulfonyl hydrazines was demonstrated in this work. By employing both anodic oxidation and cathodic reduction, a variety of 2-arylquinolines were synthesized under metal catalyst-, exogenous-oxidant-, and exogenous-reductant-free conditions.
Synthesis of sulfonylhydrazone- and acylhydrazone-substituted 8-ethoxy-3-nitro-2h-chromenes as potent antiproliferative and apoptosis inducing agents
Zhang, Datong,Ma, Yuntong,Liu, Yu,Liu, Zhao-Peng
, p. 576 - 588 (2014/08/18)
3-Nitro-2H-chromenes have recently been identified as a novel class of potent antitumor agents. In view of the favorable effects shown by sulfonylhydrazones and acylhydrazones, we designed and synthesized a series of sulfonylhydrazone- and acylhydrazone-substituted 8-ethoxy-3-nitro-2H-chromene derivatives, and evaluated their cell growth inhibition activities against A549, KG-1, A2780, and K562 cells. All the tested compounds exhibited more potent antiproliferative activity than BENC-511 against KG-1 cells. These compounds displayed IC50 values in the nanomolar range against A2780 cells. Compound 7d showed prominent cytotoxicity against K562 cells with an IC 50 of 0.11 μM, which was comparable to that of BENC-511. Compound 7d arrested K562 cells at the G1 phase at high concentrations and induced apoptosis in K562 cells. Furthermore, 7d increased the levels of cleaved caspase-3, decreased the expression of bcl-2 and induced the cleavage of poly(ADP-ribose) polymerase in K562 cells. Thus, this study provides the development of a series of novel compounds as effective antitumor agents with apoptotic death ability.
