6652-28-4

Basic information

• Product Name: BENZOIN ISOPROPYL ETHER
• Synonyms: 2-ISOPROPOXY-1,2-DIPHENYLETHANONE;2-ISOPROPOXY-2-PHENYLACETOPHENONE;2-(1-methylethoxy)-1,2-diphenyl-ethanon;2-(1-methylethoxy)-1,2-diphenyl-Ethanone;2-(1-methylethoxy)-1,2-diphenylethan-1-one;à-isopropoxy-à-phenylacetophenone;α-isopropoxy-α-phenylacetophenone;Benzoin isopropyl ether, 98+%
• CAS NO: 6652-28-4
• Molecular Formula: C₁₇H₁₈O₂
• Molecular Weight: 254.32
• EINECS: 229-677-2
• Product Categories: Industrial/Fine Chemicals;Aromatic Acetophenones & Derivatives (substituted);Functional Materials;Photopolymerization Initiators
• Mol File: 6652-28-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 78-80 °C(lit.)
• Boiling Point: 175-180 °C10 mm Hg(lit.)
• Flash Point: 152.1 °C
• Appearance: /
• Density: 1.065 g/cm³
• Vapor Pressure: 3.59E-08mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Insoluble in water
• BRN: 1977110
• CAS DataBase Reference: BENZOIN ISOPROPYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOIN ISOPROPYL ETHER(6652-28-4)
• EPA Substance Registry System: BENZOIN ISOPROPYL ETHER(6652-28-4)

Safety Data

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 6652-28-4(Hazardous Substances Data)

Usage

General Description

Benzoin isopropyl ether, also known as 2-isopropoxy-2-phenylpropan-1-one, is a chemical compound commonly used as a photoinitiator in UV-curable formulations such as inks, adhesives, and coatings. It acts as a photoinitiator by absorbing UV light and initiating a polymerization reaction, making it useful in the manufacturing of various polymer-based products. Benzoin isopropyl ether is a colorless liquid with a characteristic odor and is typically stored and handled in a well-ventilated area due to its potential for vapors to cause irritation to the respiratory system. It is important to use proper protective equipment when working with this chemical to prevent exposure and ensure safe handling.

InChI:InChI=1/C14H12O2.C6H14O/c15-13(11-7-3-1-4-8-11)14(16)12-9-5-2-6-10-12;1-5(2)7-6(3)4/h1-10,13,15H;5-6H,1-4H3

Upstream product

• 75-30-9 2-iodo-propane 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 920-39-8 isopropylmagnesium bromide 
• 134-81-6 benzil 

Downstream Products

• 1026561-51-2 ethyl (Z)-2-fluoro-4-isopropoxy-3,4-diphenylbut-2-enoate 
• 451-40-1 phenyl benzyl ketone 
• 49593-34-2 1,2-diisopropoxy-1,2-diphenylethane 
• 74121-92-9 (±)-2-isopropoxy-1,2-diphenylethan-1-ol 
• 119557-91-4 (4-Isopropoxymethyl-phenyl)-phenyl-methanone 
• 26595-40-4 α-Allyl-benzoin-iso-propylether 
• 939-48-0 isopropyl benzoate 
• 65-85-0 benzoic acid 
• 33511-55-6 meso-α,α-di-isopropoxybibenzyl 
• 33511-55-6 C₂₀H₂₆O₂ 
• 134-81-6 benzil 
• 102979-47-5 2,2-Dimethyl-3,4-diphenyl-oxetan-3-ol 
• 22568-24-7 syn-1,2-diphenyl-2-isopropoxyethanol 
• 22568-24-7 anti-1,2-diphenyl-2-isopropoxyethanol 

Relevant articles and documents

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

We report an unprecedented organocatalytic enantioselective acyloin rearrangement of α,α-disubstituted α-hydroxy acetals. In the presence of a catalytic amount of chiral binol-derived N-triflyl phosphoramide, α-hydroxy acetals rearranged to α-alkoxy ketones in good to high yields with high enantioselectivities. Formation of an ion pair between the in situ generated oxocarbenium ion and the chiral phosphoramide anion was proposed to be responsible for the highly efficient transfer of chirality. Conditions for removal of cyclohexyl and cyclopentyl groups from the corresponding α-alkoxy ketones were uncovered underpinning their potential general utility as hydroxy protecting groups. Conversion of the rearranged products to the enantioenriched α-hydroxy ketone, 1,2-diol, β-amino alcohol and 1,4-dioxane was also documented.

Bisbenzoin ethers and method of producing benzoin ethers

New bisbenzoin ethers are produced. The method of producing the bisbenzoin ethers comprises the reaction of an alkyl glycol with benzoin utilizing phosphorous oxychloride as the catalyst with hydrogen chloride as acid reacting agent. The use of phosphorous oxychloride as catalyst with hydrogen chloride improves the production of benzoin ethers in general by the reaction of benzoin with the selected alcohol.