66614-56-0

Basic information

• Product Name: 4-(2,2-diethoxyethoxy)toluene
• Synonyms: 4-(2,2-diethoxyethoxy)toluene
• CAS NO: 66614-56-0
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.2961
• EINECS: 266-426-6
• Product Categories: Aromatic Building Blocks
• Mol File: 66614-56-0.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 310.3°C at 760 mmHg
• Flash Point: 103.6°C
• Appearance: /
• Density: 0.995g/cm³
• Vapor Pressure: 0.00111mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: 4-(2,2-diethoxyethoxy)toluene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,2-diethoxyethoxy)toluene(66614-56-0)
• EPA Substance Registry System: 4-(2,2-diethoxyethoxy)toluene(66614-56-0)

Safety Data

• Hazardous Substances Data: 66614-56-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H20O3/c1-4-14-13(15-5-2)10-16-12-8-6-11(3)7-9-12/h6-9,13H,4-5,10H2,1-3H3

Upstream product

• 106-44-5 p-cresol 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 18441-43-5 5-methylbenzofuran 
• 17133-95-8 5-methyl-2-ethylbenzofuran 
• 25871-52-7 5-methyl-2-phenylbenzofuran 
• 1370283-18-3 C₁₈H₁₇N₃O₂S₂ 
• 1370283-13-8 C₁₈H₁₇N₃O₃S 
• 41964-01-6 5-p-tolyloxy-1H-pyrimidin-2-one 
• 188862-35-3 5-(bromomethyl)benzofuran 
• 67845-46-9 2-(4-methylphenoxy)acetaldehyde 

Relevant articles and documents

Enantio- and Diastereoselective, Complete Hydrogenation of Benzofurans by Cascade Catalysis

We report an enantio- and diastereoselective, complete hydrogenation of multiply substituted benzofurans in a one-pot cascade catalysis. The developed protocol facilitates the controlled installation of up to six new defined stereocenters and produces architecturally complex octahydrobenzofurans, prevalent in many bioactive molecules. A unique match of a chiral homogeneous ruthenium-N-heterocyclic carbene complex and an in situ activated rhodium catalyst from a complex precursor act in sequence to enable the presented process.

Direct Dimesitylborylation of Benzofuran Derivatives by an Iridium-Catalyzed C?H Activation with Silyldimesitylborane

Direct dimesitylborylation of benzofuran derivatives by a C?H activation catalyzed by an iridium(I)/N-heterocyclic carbene (NHC) complex in the presence of Ph2MeSi-BMes2 afforded the corresponding dimesitylborylation products in good to high yield with excellent regioselectivity. This method provides a straightforward route to donor–(π-spacer)–acceptor systems with intriguing solvatochromic luminescence properties.

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.