68162-84-5

Basic information

• Product Name: 4-METHOXY-N-(1-PHENYL-ETHYL)-BENZAMIDE
• Synonyms: TIMTEC-BB SBB005750;AKOS BB/0080;4-METHOXY-N-(1-PHENYL-ETHYL)-BENZAMIDE
• CAS NO: 68162-84-5
• Molecular Formula: C₁₆H₁₇NO₂
• Molecular Weight: 255.31
• Mol File: 68162-84-5.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-METHOXY-N-(1-PHENYL-ETHYL)-BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-N-(1-PHENYL-ETHYL)-BENZAMIDE(68162-84-5)
• EPA Substance Registry System: 4-METHOXY-N-(1-PHENYL-ETHYL)-BENZAMIDE(68162-84-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 68162-84-5(Hazardous Substances Data)

Upstream product

• 201230-82-2 carbon monoxide 
• 696-62-8 para-iodoanisole 
• 618-36-0 rac-methylbenzylamine 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 105-13-5 4-Methoxybenzyl alcohol 
• 100-42-5 styrene 
• 19226-37-0 3-(4-methoxyphenyl)-5H-1,4,2-dioxazol-5-one 
• 100-09-4 4-methoxybenzoic acid 
• 100-07-2 4-methoxy-benzoyl chloride 
• 404942-44-5 [(3aS,8aR)-3-(4-methoxybenzoyl)-3,3a,8,8a-tetrahydro-2H-indenol[1,2-d][1,3]oxazol-2-ylidene]cyanamide 
• 178313-97-8 (S)-N-(1-phenylethyl)-2-methylideneaziridine 
• 28099-28-7 4-hydroxy-4'-[(p-methoxy)benzoyloxy]phenyl 
• 701-53-1 p-methoxybenzoyl fluoride 
• 7465-88-5 4-methoxy-N-phenylbenzamide 

Downstream Products

• 874-90-8 4-methoxybenzonitrile 

Relevant articles and documents

Fluorinated solvent-assisted photocatalytic aerobic oxidative amidation of alcoholsviavisible-light-mediated HKUST-1/Cs-POMoW catalysis

Considering the irreplaceable importance of photocatalytic functionalization reactions and the widespread attention paid to the use of metal-organic frameworks, especially their modified variants, for this purpose in recent years, different types of HKUST-1/POMoW composites were prepared through the immobilization of a series of Keggin-type polyoxometalates (POMs; POW = H3PW12O40, POMo = H3PMo12O40, and POMoW = H3PMo6W6O40) on HKUST-1 as a metal-organic framework (HKUST-1; Cu3(1,3,5-benzenetricarboxilicacid)2). Then, to produce HKUST-1/Cs-POM, the substitution of H+cations with Cs+ones as counter cations was carried out. The prepared composites were fully characterized with the PXRD (powder X-ray diffraction), FT-IR (Fourier transform infrared spectroscopy), BET and BJH (sorption of N2), TGA (thermo-gravimetric analysis), SEM (scanning electron microscopy), EDX (energy dispersive X-ray), TEM (transmission electron microscopy), UV-vis DRS (diffuse reflectance UV-vis spectroscopy), photoluminescence (PL) spectroscopy and ICP-AES (inductively coupled plasma atomic emission spectroscopy) techniques. The great importance?of the amide functional group and the attractiveness of photocatalytic oxidative functionalization?reactions led us to study the formation of this functional group using the prepared catalytic system in line with our previous research in this field. The HKUST-1/Cs-POMoW composite showed a raised photocatalytic performance compared to the discrete components, HKUST-1 and Cs-POMs, in aerobic oxidative amidation of alcohols under illumination with visible light, owing to the presence of catalytically active Cs-POMs deposited on the MOF particles. Besides, the combination of composite components mitigated the recombination rate of the electron-hole pairs, raising its photocatalytic activity. The attractiveness of fluorine solvents for oxidation reactions has led to the study of their role in the efficiency of oxidative amidation of alcohols and their significant effect on the efficiency of the process has been confirmed. The Cu-MOF/POM catalyst showed excellent stability during the reaction, and no significant decrease in its ability was observed during five consecutive cycles.

Oxidative amidation by Cu(ii)-guanidine acetic acid immobilized on magnetized sawdust with eggshell as a natural base

Copper(ii)-guanidine acetic acid complex was immobilized on the surface of magnetized raw waste sawdust (SD) as an abundant natural biopolymer and employed as an efficient and recoverable catalyst in oxidative amidation reaction, while waste eggshell (ES) powder was used as a low-cost solid base. The magnetic raw catalyst was fully characterized using FTIR, XRD, SEM, EDX, TGA, and VSM. A variety of amide derivatives were successfully synthesized in moderate to good yields using benzyl alcohol and amine salts. The application of sawdust and eggshell as two natural and abundant waste materials is the main advantage of this research. Moreover, these low-cost catalysts were recovered at least five times and utilized in reaction systems with a minimal decrease in activity.

Nickel/Briphos-Catalyzed Direct Transamidation of Unactivated Secondary Amides Using Trimethylsilyl Chloride

Direct transamidation of secondary amides was developed via nickel catalysis. In the presence of trimethylsilyl chloride and manganese, Ni(diglyme)Cl2 with a Briphos ligand efficiently promoted the transamidation of N-aryl benzamide derivatives with primary amines to afford the corresponding secondary amides in moderate to good yields. Primary amines bearing electron-donating groups gave higher yields of the transamidation products.