68485-53-0

Basic information

• Product Name: 4-allyl-1-(1-hydroxy-1-benzyloxycarbonylmethyl)-azetidin-2-one
• Synonyms: 4-allyl-1-(1-hydroxy-1-benzyloxycarbonylmethyl)-azetidin-2-one
• CAS NO: 68485-53-0
• Molecular Weight: 275.304
• Mol File: 68485-53-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-allyl-1-(1-hydroxy-1-benzyloxycarbonylmethyl)-azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-allyl-1-(1-hydroxy-1-benzyloxycarbonylmethyl)-azetidin-2-one(68485-53-0)
• EPA Substance Registry System: 4-allyl-1-(1-hydroxy-1-benzyloxycarbonylmethyl)-azetidin-2-one(68485-53-0)

Safety Data

• Hazardous Substances Data: 68485-53-0(Hazardous Substances Data)

Upstream product

• 930-21-2 2-azetidinone 
• 68485-52-9 4-allylazetidin-2-one 
• 591-93-5 1,4-Pentadiene 
• 52709-42-9 benzylglyoxylate 

Downstream Products

• 79683-54-8 (2RS,6RS)-benzyl 4-methyl-8-oxo-1,3-diazabicyclo<4.2.0>oct-3-ene-2-carboxylate 
• 79683-54-8 (2RS,6SR)-benzyl 4-methyl-8-oxo-1,3-diazabicyclo<4.2.0>oct-3-ene-2-carboxylate 
• 112213-53-3 (2RS,6SR)-4-methyl-8-oxo-1,3-diazabicyclo<4.2.0>oct-3-ene-2-carboxylic acid 
• 72658-70-9 benzyl 7-oxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 72658-70-9 benzyl 7-oxo-1-azabicyclo<3.2.0>heptane-2-carboxylate 
• 67501-71-7 benzyl 7-oxo-1-azabicyclo[3.2.0] hept-2-ene-2-carboxylate 
• 68485-45-0 4-allyl-1-(1-benzyloxycarbonyl-1-triphenylphosphoranylidenemethyl)-azetidin-2-one 
• 79683-54-8 (2S,6R)-4-Methyl-8-oxo-1,3-diaza-bicyclo[4.2.0]oct-3-ene-2-carboxylic acid benzyl ester 
• 79669-39-9 4-allyl-1-azetidin-2-one 
• 79669-46-8 (2-Allyl-4-oxo-azetidin-1-yl)-chloro-acetic acid benzyl ester 

Relevant articles and documents

4-Allyl azetidinone intermediate for β-lactam antibacterial agents

Compounds are provided of the formula (II): STR1 wherein R1 is a group such that CO2 R1 is an ester group and A1 is a hydrogen atom or a methyl group. These compounds possess antibacterial activity. The preparat

Olivanic Acid Analogues. Part 1. Total Synthesis of the 7-Oxo-1-azabicyclohept-2-ene-2-carboxylate System and Some Related β-Lactams

4-Allylazetidin-2-one, prepared from penta-1,4-diene and chlorosulphonyl isocyanate, has been used to synthesise the parent 7-oxo-1-azabicyclohept-2-ene-2-carboxylate system of the naturally occurring olivanic acids, using an intramolecular Wittig reaction to construct the 2,3-double bond.Cyclisation of ketones derived from the 4-allyl grouping produced 3-substituted derivatives, while use of the azetidin-2-one prepared from hexa-1,5-diene and chlorosulphonyl isocyanate has given the homologous 8-oxo-1-azabicyclooct-2-ene system.

Bicyclic β-lactam antibiotics

Compounds of the formula (I): STR1 wherein G is hydrogen, alkyl, alkenyl, substituted alkyl or substituted alkenyl, R1 is alkyl or aryl, substituted alkyl or substituted aryl, and R is an organic group such that --CO2 R is an ester group are produced. The compounds are useful as antibacterial and β-lactamase inhibitory agents.