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686718-85-4

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686718-85-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 686718-85-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,6,7,1 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 686718-85:
(8*6)+(7*8)+(6*6)+(5*7)+(4*1)+(3*8)+(2*8)+(1*5)=224
224 % 10 = 4
So 686718-85-4 is a valid CAS Registry Number.

686718-85-4Downstream Products

686718-85-4Relevant articles and documents

An improved synthesis of the scyphostatin side-chain

McAllister, Graeme D.,Taylor, Richard J. K.

, p. 2551 - 2554 (2004)

A formal synthesis of the lipophilic side-chain of scyphostatin has been achieved using a convergent synthesis, in 16% yield over six steps. This synthesis involves enzymatic desymmetrisation of a meso-diol, resolution of 2-methylbutan-1-ol, stereoselective hydrozirconation of a volatile acetylene and a Negishi-style cross coupling.

Total synthesis of (+)-scyphostatin, a potent and specific inhibitor of neutral sphingomyelinase

Inoue, Munenori,Yokota, Wakako,Murugesh, Modachur G.,Izuhara, Takashi,Katoh, Tadashi

, p. 4207 - 4209 (2007/10/03)

The five crucial steps in the first total synthesis of (+)-scyphostatin from D-arabinose involve (see picture): a) stereoselective aldol coupling to form a quaternary stereocenter, b) ring-closing metathesis (RCM) to construct the cyclohexene ring, c) Neg

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