70319-43-6

Basic information

• Product Name: 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)-
• CAS NO: 70319-43-6
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Mol File: 70319-43-6.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)-(70319-43-6)
• EPA Substance Registry System: 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)-(70319-43-6)

Safety Data

• Hazardous Substances Data: 70319-43-6(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 2550-26-7 4-Phenyl-2-butanone 
• 16520-62-0 4-Phenyl-1-butyne 
• 75-24-1 trimethylaluminum 
• 541-41-3 chloroformic acid ethyl ester 
• 74-88-4 methyl iodide 
• 4341-76-8 Ethyl 2-butynoate 
• 917-54-4 methyllithium 

Downstream Products

• 55066-44-9 3-methyl-5-phenylpent-2-en-1-ol 
• 107647-42-7 trans-3-Methyl-5-phenyl-2-pentenal 
• 107647-47-2 cis-3-Methyl-5-phenyl-2-pentenal 
• 72681-07-3 (E)-4-methyl-6-phenyl-hex-3-en-2-one 
• 55053-55-9 (S)-ethyl 3-methyl-5-phenylpentanoate 
• 41927-33-7 (S)-(-)-3-methyl-5-phenylpentan-1-ol 
• 942416-34-4 (S)-(-)-3-methyl-5-phenylpentanaldehyde 
• 55066-48-3 3-methyl-5-phenylpentan-1-ol 
• 55053-55-9 (+)-(R)-ethyl 3-methyl-5-phenylpentanoate 
• 55053-55-9 ethyl 5-phenyl-3-methyl-2-pentanoate 
• 1431460-73-9 diethyl (Z)-3-methyl-5-phenyl-2-pentenyl phosphate 
• 1638110-77-6 (Z)-(5-chloro-3-methyl-3-penten-1-yl)benzene 
• 1239568-96-7 ethyl (S)-3-methyl-5-phenyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate 

Relevant articles and documents

Air-Stable PdI Dimer Enabled Remote Functionalization: Access to Fluorinated 1,1-Diaryl Alkanes with Unprecedented Speed

While remote functionalization via chain walking has the potential to enable access to molecules via novel disconnections, such processes require relatively long reaction times and can be in need of elevated temperatures. This work features a remote arylation in less than 10 min reaction time at room temperature over a distance of up to 11 carbons. The unprecedented speed is enabled by the air-stable PdI dimer [Pd(μ-I)(PCy2tBu)]2, which in contrast to its PtBu3 counterpart does not trigger direct coupling at the initiation site, but regioconvergent and chemoselective remote functionalization to yield valuable fluorinated 1,1-diaryl alkanes. Our combined experimental and computational studies rationalize the origins of switchability, which are primarily due to differences in dispersion interactions.

Cobalt-Catalyzed Asymmetric 1,4-Hydroboration of Enones with HBpin

Herein, a series of new 8-OIQ cobalt complexes were synthesized and used for cobalt-catalyzed chemo- and enantioselective 1,4-hydroboration of enones with HBpin to access chiral β,β-disubstituted ketones with good to excellent chemo- and enantioselectivties. This protocol is operationally simple and shows a broad substrate scope.

Copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters with chiral phenol–carbene ligands

A chiral phenol–NHC ligand enabled the copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters. The phenol moiety of the chiral NHC ligand played a critical role in producing the enantiomerically enriched products. The catalyst worked well for various (Z)-isomer substrates. Opposite enantiomers were obtained from (Z)- and (E)-isomers, with a higher enantiomeric excess from the (Z)-isomer.