736170-70-0

Basic information

• Product Name: (2S)-3-tert-butoxy-2-[(2R)-2-mercapto-3-phenyl-propionylamino]-propionic acid tert-butyl ester
• Synonyms: (2S)-3-tert-butoxy-2-[(2R)-2-mercapto-3-phenyl-propionylamino]-propionic acid tert-butyl ester
• CAS NO: 736170-70-0
• Molecular Weight: 381.536
• Mol File: 736170-70-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S)-3-tert-butoxy-2-[(2R)-2-mercapto-3-phenyl-propionylamino]-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-3-tert-butoxy-2-[(2R)-2-mercapto-3-phenyl-propionylamino]-propionic acid tert-butyl ester(736170-70-0)
• EPA Substance Registry System: (2S)-3-tert-butoxy-2-[(2R)-2-mercapto-3-phenyl-propionylamino]-propionic acid tert-butyl ester(736170-70-0)

Safety Data

• Hazardous Substances Data: 736170-70-0(Hazardous Substances Data)

Upstream product

• 57359-76-9 (2R)-2-(acetylthio)-3-phenylpropanoic acid 
• 63-91-2 L-phenylalanine 
• 48067-24-9 O-tert-butyl L-serine tert-butyl ester 
• 84800-12-4 (R)-2-mercapto-3-phenylpropanoic acid 

Downstream Products

• 736170-76-6 (2S)-3-tert-butoxy-2-{(2R)-2-[(2S)-2-tert-butoxy-carbonylamino-4-methylsulfanyl-butyrylsulfanyl]-3-phenyl-propionylamino}-propionic acid tert-butyl ester 

Relevant articles and documents

Design and synthesis of chromogenic thiopeptolide substrates as MetAPs active site probes

Twenty one chromogenic thiopeptolide substrates were designed and synthesized as the active site probes and analyzed with each S1 site of mutant residues and enzymes of wild-type MetAP1s. The preliminary enzymatic experiments indicate that cysteine 70 or 202, at either Escherichia coli or human MetAP1, played a crucial role in the methionine hydrolysis.