7376-90-1

Basic information

• Product Name: Z-D-PHE-NH2
• Synonyms: AC-PHE-NH2;AC-PHENYLALANINE-NH2;ACETYL-L-PHENYLALANINE AMIDE;N-ALPHA-L-PHENYLALANINE;N-ALPHA-CARBOBENZOXY-D-PHENYLALANINE AMIDE;N-ACETYL-L-PHE NH2;Z-D-PHE-NH2;Z-D-PHENYLALANINE AMIDE
• CAS NO: 7376-90-1
• Molecular Formula: C₁₁H₁₄N₂O₂
• Molecular Weight: 206.24
• Product Categories: Amino Acid Derivatives;Amino Acids
• Mol File: 7376-90-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 503.1oC at 760 mmHg
• Flash Point: 258oC
• Appearance: /
• Density: 1.152g/cm3
• Vapor Pressure: 3.01E-10mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: Z-D-PHE-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-PHE-NH2(7376-90-1)
• EPA Substance Registry System: Z-D-PHE-NH2(7376-90-1)

Safety Data

• Hazardous Substances Data: 7376-90-1(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C11H14N2O2/c1-8(14)13-10(11(12)15)7-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H2,12,15)(H,13,14)/t10-/m0/s1

Upstream product

• 38243-38-8 α-N-acetylaminocinnamamide 
• 5241-56-5 benzyl [(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate 
• 1161-13-3 N-Cbz-L-Phe 
• 63-91-2 L-phenylalanine 
• 17193-31-6 (R,S)-2-amino-3-phenylpropionamide 
• 141-78-6 ethyl acetate 
• 5241-58-7 L-Phenylalanine amide 
• 108-24-7 acetic anhydride 
• 78422-10-3 (Z)-2-acetylamino-3-phenylprop-2-enamide 
• 13649-97-3 (S)-4-benzyl-2-methyl-4H-oxazol-5-one 

Downstream Products

• 1147100-77-3 C₁₃H₁₇N₂O₃PS₂ 
• 83291-07-0 (-)-(S)-N-(1-cyano-2-phenyl-ethyl)-acetamide 
• 87784-07-4 2-methyl-4-benzyl-5-oxazole 
• 87784-08-5 2-methyl-4-benzyl-5-(N-((p-benzyloxyphenyl)ethyl)acetamido)oxazole 
• 87783-75-3 2-methyl-4-benzyl-5-acetamidooxazole 
• 87784-06-3 2-methyl-4-benzyl-5-(trifluoroacetamido)oxazole 
• 2018-61-3 (S)-2-acetylamino-3-phenylpropanoic acid 

Relevant articles and documents

Hybrid catalysis of 8-quinolinecarboxaldehyde and br?nsted acid for efficient racemization of α-amino amides and its application in chemoenzymatic dynamic kinetic resolution

The combination of 8-quinolinecarboxaldehyde and benzoic acid proved to be an effective catalyst system for the racemization of N-unprotected α-aryl- or α-alkyl-substituted α-amino amides. Application of this system to chemoenzymatic dynamic kinetic resolution provided an efficient access to enantiomerically pure N-acetyl-α-amino amides in good to high yields.

Method for preparing optically active amines

The present invention relates to a method of preparing optically active amines and chiral amines prepared thereby. The method includes reacting an amine compound, a metal catalyst, a biocatalyst including a lipase, and an acyl donor compound in an organic solvent to obtain a chiral amide compound, and then hydrolyzing the chiral amide compound to obtain a chiral amine.

Dynamic kinetic resolution of primary amines with a recyclable Pd nanocatalyst for racemization

(Chemical Equation Presented) A practical procedure for the dynamic kinetic resolution (DKR) of primary amines has been developed. This procedure employs a palladium nanocatalyst as the racemization catalyst, a commercial lipase (Novozym-435) as the resol