7498-40-0

Basic information

• Product Name: (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE
• Synonyms: (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE;TIMTEC-BB SBB006377;4-nitro-N-(2-pyridyl)benzamide;4-Nitro-N-2-pyridinylbenzamide;4-nitro-N-pyridin-2-ylbenzamide;4-Nitro-N-pyridin-2-yl-benzamide;Benzamide, 4-nitro-N-2-pyridinyl-
• CAS NO: 7498-40-0
• Molecular Formula: C₁₂H₉N₃O₃
• Molecular Weight: 243.22
• Mol File: 7498-40-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 361°Cat760mmHg
• Flash Point: 172.1°C
• Appearance: /
• Density: 1.402g/cm³
• Vapor Pressure: 2.14E-05mmHg at 25°C
• Refractive Index: 1.679
• CAS DataBase Reference: (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE(7498-40-0)
• EPA Substance Registry System: (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE(7498-40-0)

Safety Data

• Hazardous Substances Data: 7498-40-0(Hazardous Substances Data)

Usage

General Description

(4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE is a chemical compound that is commonly used in organic synthesis and as an intermediate in the production of various pharmaceuticals and agrochemicals. It is a yellow to brown crystalline solid with a molecular formula C12H9N3O3. (4-NITROPHENYL)-N-(2-PYRIDYL)FORMAMIDE has been studied for its potential applications in the treatment of various diseases, including cancer. It has also been investigated for its antimicrobial properties and as a building block for the synthesis of other complex organic molecules. Additionally, it has been used in the development of novel materials and as a reagent in chemical reactions.

InChI:InChI=1/C12H9N3O3/c16-12(14-11-3-1-2-8-13-11)9-4-6-10(7-5-9)15(17)18/h1-8H,(H,13,14,16)

Upstream product

• 504-29-0 2-aminopyridine 
• 122-04-3 4-nitro-benzoyl chloride 
• 5918-77-4 2-<(p-nitrobenzylidene)amino>pyridine 
• 86843-82-5 p-nitrobenzoyl chloride 
• 555-16-8 4-nitrobenzaldehdye 
• 62-23-7 4-nitro-benzoic acid 
• 109-09-1 2-chloropyridine 
• 619-80-7 4-nitrobenzamide 
• 14150-95-9 2-aminopyridine N-oxide 
• 100-19-6 (4-nitrophenyl)ethanone 
• 100-12-9 4-ethylnitrobenzene 

Downstream Products

• 686290-12-0 (1-naphthyl)[N-(2-pyridyl)-4-nitrobenzamido](triphenylphosphine)nickel(II) 
• 1261035-37-3 N-(pyridin-2-yl)-4-stearamidobenzamide 
• 96830-01-2 N-Methyl-4-nitro-N-pyridin-2-yl-benzamide 
• 1372892-86-8 4-((3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)-N-(pyridin-2-yl)benzamide 
• 1261035-36-2 N-(pyridine-2-yl)-4-dodecanamido-benzamide 
• 86843-89-2 2-[5-(4-Nitro-phenyl)-tetrazol-1-yl]-pyridine 
• 86843-97-2 2-(4-Nitro-phenyl)-[1,2,4]triazolo[1,5-a]pyridine 
• 7467-42-7 4-amino-N-(pyridin-2-yl)benzamide 

Relevant articles and documents

Direct Transformation of Alkylarenes into N-(Pyridine-2-yl)amides by C(sp3)–C(sp3) Bond Cleavage

C(sp3)–H bond functionalization and C(sp3)–C(sp3) bond cleavage are very challenging transformations in chemistry. Herein, we report a mild and green methodology for the construction of N-(pyridine-2-yl)amides via tandem C(sp3)–H activation/C–C bond cleavage of alkylarenes. Various N-heterocyclic amides were directly synthesized from alkylarenes in water in moderate to good yields.

CuI incorporated cobalt ferrite nanoparticles as a magnetically separable catalyst for oxidative amidation reaction

A Cu-incorporated magnetic nanocatalyst (CoFe2O4?SiO2-SH-CuI) has been developed by immobilizing CuI on the modified surface of CoFe2O4 magnetic nanoparticles. The surface of the silica coated cobalt

Metal-Free Synthesis of N-(Pyridine-2-yl)amides from Ketones via Selective Oxidative Cleavage of C(O)-C(Alkyl) Bond in Water

The TBHP/TBAI-mediated synthesis of N-(pyridine-2-yl)amides in water from ketones and 2-aminopyridine via direct oxidative C-C bond cleavage has been developed. A series of ketones, including more challenging inactive aromatic ketones substituted with div