75629-19-5

Basic information

• Product Name: kuwanon G
• Synonyms: kuwanon G;8-[(1S)-6α-(2,4-Dihydroxybenzoyl)-5β-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1β-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;Albanin F;Moracenin B;NSC 356888;kuwanone G
• CAS NO: 75629-19-5
• Molecular Formula: C₄₀H₃₆O₁₁
• Molecular Weight: 692.70724
• Product Categories: reagent;standard substance
• Mol File: 75629-19-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 942.4°C at 760 mmHg
• Flash Point: 293.9°C
• Appearance: /
• Density: 1.446g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.707
• PKA: 6.54±0.40(Predicted)
• CAS DataBase Reference: kuwanon G(CAS DataBase Reference)
• NIST Chemistry Reference: kuwanon G(75629-19-5)
• EPA Substance Registry System: kuwanon G(75629-19-5)

Safety Data

• Hazardous Substances Data: 75629-19-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity.

InChI:InChI=1/C40H36O11/c1-18(2)4-8-26-38(50)36-33(48)17-32(47)35(40(36)51-39(26)25-11-7-22(43)16-31(25)46)28-13-19(3)12-27(23-9-5-20(41)14-29(23)44)34(28)37(49)24-10-6-21(42)15-30(24)45/h4-7,9-11,13-17,27-28,34,41-48H,8,12H2,1-3H3/t27?,28-,34-/m0/s1

Upstream product

• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 91-52-1 2,4 dimethoxybenzoic acid 
• 39828-35-8 2,4-dimethoxybenzoyl chloride 
• 59656-68-7 1-(2-hydroxy-3-iodo-4,6-dimethoxyphenyl)ethan-1-one 
• 90-24-4 2-hydroxy-4,6-dimethoxyacetophenone 
• 78-80-8 2-methylbut-1-en-3-yne 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 79004-61-8 (E)-2-(2,4-dimethoxyphenyl)-5,7-dimethoxy-3-(3-methylbut-2-en-1-yl)-8-(3-methylbuta-1,3-dien-1-yl)-4H-chromen-4-one 
• 1218939-24-2 (E)-3-(2,4-dimethoxyphenyl)-1-(4-methoxy-2-[(3-methylbut-2-en-1-yl)oxy]phenyl)prop-2-en-1-one 
• 36685-67-3 (E)-1-(2-hydroxy-4-methoxyphenyl)-3-(2,4-dimethoxyphenyl)prop-2-en-1-one 

Downstream Products

• 75629-23-1 2-(2,4-Dimethoxy-phenyl)-8-[5-(2,4-dimethoxy-phenyl)-6-(2-hydroxy-4-methoxy-benzoyl)-3-methyl-cyclohex-2-enyl]-5-hydroxy-7-methoxy-3-(3-methyl-but-2-enyl)-chromen-4-one 
• 75629-25-3 2-(2,4-Dimethoxy-phenyl)-8-[5-(2,4-dimethoxy-phenyl)-6-(2-hydroxy-4-methoxy-benzoyl)-3-methyl-cyclohex-2-enyl]-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one 
• 75629-24-2 8-[6-(2,4-Dimethoxy-benzoyl)-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5-hydroxy-7-methoxy-3-(3-methyl-but-2-enyl)-chromen-4-one 
• 75629-26-4 8-[6-(2,4-Dimethoxy-benzoyl)-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one 
• 75629-26-4 8-[(1S,5R,6S)-6-(2,4-Dimethoxy-benzoyl)-5-(2,4-dimethoxy-phenyl)-3-methyl-cyclohex-2-enyl]-2-(2,4-dimethoxy-phenyl)-5,7-dimethoxy-3-(3-methyl-but-2-enyl)-chromen-4-one 

Relevant articles and documents

Total Synthesis of Mulberry Diels-Alder-Type Adducts Kuwanons G and H

Mulberry Diels-Alder-type adducts (MDAAs) are a group of rare natural polyphenols biosynthetically derived from [4 + 2]-cycloaddition of chalcones and dehydroprenylphenols. In this study, kuwanons G (1) and H (2), two bioactive MDAAs with unique dehydroprenylflavonoid dienes, were totally synthesized for the first time in a biomimetic manner. The key features of the convergent route include the use of the Baker-Venkataraman rearrangement, alkylation of β-diketone, intramolecular cyclization, and Suzuki-Miyaura coupling to achieve the subunit diene.