79175-35-2

Basic information

• Product Name: 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE
• Synonyms: 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE;3,4-DICHLOROPHENYLMAGNESIUM BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN;3,4-Dichlorophenylmagnesium Bromide 1.0 M In Diethyl Ether;3,4-dichlorophenylmagnesium bromide solution;3,4-Dichlorophenylmagnesium bromide solution 0.5 in THF;3,4-Dichlorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal;3,4-DichlorophenylMagnesiuM broMide, 0.50M in 2-MeTHF;3,4-DichlorophenylMagnesiuM broMide solution 0.5 M in THF
• CAS NO: 79175-35-2
• Molecular Formula: C₆H₃BrCl₂Mg
• Molecular Weight: 250.2
• Product Categories: Aryl;Grignard Reagents;Organometallic Reagents
• Mol File: 79175-35-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 180.5°C at 760 mmHg
• Flash Point: 1 °F
• Appearance: Yellow to brown/Liquid
• Density: 0.980 g/mL at 25 °C
• Vapor Pressure: 1.21mmHg at 25°C
• Storage Temp.: 2-8°C
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE(79175-35-2)
• EPA Substance Registry System: 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE(79175-35-2)

Safety Data

• Hazard Codes: F,C,Xn
• Statements: 11-14-19-22-34-40-36/37
• Safety Statements: 16-26-33-36/37/39-45-36/37
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• HazardClass: 3
• Hazardous Substances Data: 79175-35-2(Hazardous Substances Data)

Usage

General Description

3,4-Dichlorophenylmagnesium bromide is a chemical compound used in organic synthesis as a reagent for the introduction of the 3,4-dichlorophenyl group in various organic compounds. It is a strong nucleophile and can react with a wide range of electrophiles, including carbonyl compounds, alkyl halides, and epoxides. 3,4-DICHLOROPHENYLMAGNESIUM BROMIDE is commonly used in Grignard reactions, where it adds the 3,4-dichlorophenyl group to organic molecules, allowing for the creation of new carbon-carbon bonds. It is also used in the preparation of pharmaceuticals, agrochemicals, and other organic compounds. Additionally, 3,4-Dichlorophenylmagnesium bromide is highly reactive and requires careful handling and storage due to its sensitivity to air and moisture.

InChI:InChI=1/C6H3Cl2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q-1;;+2/p-1

Upstream product

• 18282-59-2 4-bromo-1,2-dichlorobenzene 
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Downstream Products

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• 100199-37-9 (1S,2S)-1-(3,4-Dichloro-phenyl)-2-[1,2,4]triazol-1-yl-cycloheptanol 
• 144451-69-4 3-(3-Chloro-phenyl)-2-cyano-3-(3,4-dichloro-phenyl)-propionic acid methyl ester 
• 100199-36-8 (1S,2S)-1-(3,4-Dichloro-phenyl)-2-[1,2,4]triazol-1-yl-cyclohexanol 
• 100199-36-8 (1S,2R)-1-(3,4-Dichloro-phenyl)-2-[1,2,4]triazol-1-yl-cyclohexanol 
• 143965-99-5 dicholoropane 
• 21270-03-1 4-[2-Bromo-1-(2-ethyl-hexyloxy)-ethyl]-1,2-dichloro-benzene 
• 267884-77-5 (1S,R,4S)-N,N-(dibenzyl)-4-amino-1-(3,4-dichlorophenyl)-4-phenyl-1-butanol 
• 851337-42-3 2-(3,4-dichloro-phenyl)-cyclohexanol 
• 131112-05-5 bis(3,4-dichlorophenyl)borinic acid 
• 949568-31-4 (R)-1,2-dichloro-4-(1-phenylallyl)benzene 
• 946412-73-3 1-(3,4-dichlorophenyl)-4-(3,4-dimethoxyphenyl)butan-1-ol 
• 949568-47-2 (R,E)-methyl 4-(3,4-dichlorophenyl)-4-phenylbut-2-enoate 

Relevant articles and documents

SELECTIVE INHIBITOR OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)

The disclosure is directed to crystalline forms of the compound of Formula I, pharmaceutically acceptable salts of the compound of Formula I, and crystalline forms thereof. Pharmaceutical compositions comprising said crystalline forms and salts, as well a

(3,4-DICHLORO-PHENYL)-((S)-3-PROPYL-PYRROLIDIN-3-YL)-METHANONE HYDROCHLORIDE AND MANUFACTURING PROCESSES

The present invention is concerned with a novel process for the preparation of a compound of formula I and its hydrates, as well as with a crystall polymorph thereof. The compounds of formula (I) and the corresponding hydrates are pharmaceutically active substances.