80407-74-5

Basic information

• Product Name: N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine
• Synonyms: N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine
• CAS NO: 80407-74-5
• Molecular Weight: 573.611
• Mol File: 80407-74-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine(80407-74-5)
• EPA Substance Registry System: N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine(80407-74-5)

Safety Data

• Hazardous Substances Data: 80407-74-5(Hazardous Substances Data)

Upstream product

• 53054-01-6 (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid tert-butyl ester 
• 19741-14-1 4-[(2,4-diaminopteridin-6-ylmethyl)methylamino]benzoic acid 
• 56892-71-8 4-[(2,4-diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoic O-isobutyl-carbonic anhydride 
• 80407-76-7 N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-N^δ-carbobenzoxy-L-ornithine tert-butyl ester 

Downstream Products

• 80407-73-4 N^α-(4-amino-4-deoxy-N¹⁰-methylpteroyl)-L-ornithine 

Relevant articles and documents

Lysine and Ornithine Analogues of Methotrexate as Inhibitors of Dihydrofolate Reductase

The ornithine (6a) and lysine (6b) analogues of methotrexate (1) have been synthesized via condensation of 4-amino-4-deoxy-N10-methylpteroic acid (2) with Nδ-carbobenzoxy-L-ornithine tert-butyl ester (3a) and Nε-carbobenzo