80795-00-2 Usage
Description
[R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester, also known as dipalmitoyl phosphatidic acid, is a phospholipid derivative that plays a crucial role in biological systems. It consists of two palmitic acid chains esterified at the 1and 2-positions of glycerol and a phosphoric acid dibenzyl ester at the 3-position. [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester is commonly found in the cell membranes of animals and is involved in various cellular processes, including cell signaling, membrane transport, and lipid metabolism. It also acts as a precursor for the production of other important lipid molecules. Due to its biological significance and potential therapeutic properties, dipalmitoyl phosphatidic acid is widely used in research and pharmaceutical applications.
Uses
Used in Pharmaceutical Applications:
[R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester is used as a pharmaceutical compound for its role in cellular processes. Its presence in cell membranes and involvement in cell signaling, membrane transport, and lipid metabolism make it a valuable component in the development of drugs targeting these pathways.
Used in Research Applications:
In the field of research, [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester is used as a research tool for studying the structure and function of cell membranes. Its role as a precursor for the production of other lipid molecules also makes it an important compound for investigating lipid metabolism and related cellular processes.
Used in Drug Delivery Systems:
Similar to gallotannin, [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester can be employed in the development of novel drug delivery systems. Its incorporation into these systems may enhance the delivery, bioavailability, and therapeutic outcomes of various drugs, particularly those targeting cellular processes in which this phospholipid derivative is involved.
Used in Cosmetics Industry:
[R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester is used as an ingredient in the cosmetics industry for its potential moisturizing and emollient properties. Its presence in cell membranes and its role in lipid metabolism may contribute to the maintenance of skin health and hydration.
Used in the Food Industry:
In the food industry, [R,(+)]-1-O,2-O-Dipalmitoyl-L-glycerol 3-(phosphoric acid dibenzyl) ester may be used as an additive for its emulsifying properties. This can help improve the texture, stability, and shelf life of various food products by promoting the formation of stable emulsions.
Check Digit Verification of cas no
The CAS Registry Mumber 80795-00-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,7,9 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 80795-00:
(7*8)+(6*0)+(5*7)+(4*9)+(3*5)+(2*0)+(1*0)=142
142 % 10 = 2
So 80795-00-2 is a valid CAS Registry Number.
80795-00-2Relevant articles and documents
Phospholipids Chiral at Phosphorus. 5. Synthesis and Configurational Analysis of Chiral Phosphatidylethanolamine
Bruzik, Karol,Tsai, Ming-Daw
, p. 747 - 754 (2007/10/02)
We report the synthesis and configurational analysis of 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) chirally labeled with 17O and 18O at the phosphate head group.Condensation of (S)-1,2-dipalmitoyl-sn-glycerol, P17OCl3, and N-(1-phenylethyl)-2-aminoethanol gives a diastereomeric mixture of cyclic oxazaphospholidines.The two diastereomers were separated by coloumn chromatography.Ring opening with H218O followed by hydrogenolysis with H2/Pd gives (Rp)- and (Sp)-DPPE.The relative configuration and isotopic enrichments of DPPE can be analyzed by 31P NMR following silylation of DPPE.To determine the absolute configuration, the two diastereomers of DPPE are converted, by a combined organic and biochemical procedure, into (Rp)- and (Sp)-1-phospho-(R)-propane-1,2-diol, with all P-O bonds intact.The configuration of the latter compound is then analyzed by 31P NMR as reported previously (Buchwald, S.L.; Knowles, J.R.J.Am.Chem.Soc. 1980, 102, 6601-6603).
