88035-57-8

Basic information

• Product Name: Hexadecanoic acid, 2-[[bis(phenylmethoxy)phosphinyl]oxy]-1-methylethyl ester, (R)-
• CAS NO: 88035-57-8
• Molecular Formula: C33H51O6P
• Molecular Weight: 574.738
• Mol File: 88035-57-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Hexadecanoic acid, 2-[[bis(phenylmethoxy)phosphinyl]oxy]-1-methylethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexadecanoic acid, 2-[[bis(phenylmethoxy)phosphinyl]oxy]-1-methylethyl ester, (R)-(88035-57-8)
• EPA Substance Registry System: Hexadecanoic acid, 2-[[bis(phenylmethoxy)phosphinyl]oxy]-1-methylethyl ester, (R)-(88035-57-8)

Safety Data

• Hazardous Substances Data: 88035-57-8(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 80795-00-2 dibenzyl 1,2-dipalmitoyl-sn-glycero-3-phosphate 
• 30334-71-5 1,2-dipalmitoyl-sn-glycerol 
• 908094-04-2 phenyldiazomethane 
• 923-61-5 1,2-dipalmitoyl-3-sn-phosphatidylethanolamine 
• 7091-44-3 1,2-dipalmitoyl-sn-glycero-3-phosphatidic acid 
• 88035-56-7 dibenzyl 2-palmitoyl-sn-glicero-3-phosphate 

Relevant articles and documents

Phospholipids Chiral at Phosphorus. 5. Synthesis and Configurational Analysis of Chiral Phosphatidylethanolamine

We report the synthesis and configurational analysis of 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) chirally labeled with 17O and 18O at the phosphate head group.Condensation of (S)-1,2-dipalmitoyl-sn-glycerol, P17OCl3, and N-(1-phenylethyl)-2-aminoethanol gives a diastereomeric mixture of cyclic oxazaphospholidines.The two diastereomers were separated by coloumn chromatography.Ring opening with H218O followed by hydrogenolysis with H2/Pd gives (Rp)- and (Sp)-DPPE.The relative configuration and isotopic enrichments of DPPE can be analyzed by 31P NMR following silylation of DPPE.To determine the absolute configuration, the two diastereomers of DPPE are converted, by a combined organic and biochemical procedure, into (Rp)- and (Sp)-1-phospho-(R)-propane-1,2-diol, with all P-O bonds intact.The configuration of the latter compound is then analyzed by 31P NMR as reported previously (Buchwald, S.L.; Knowles, J.R.J.Am.Chem.Soc. 1980, 102, 6601-6603).