85217-77-2

Basic information

• Product Name: 4-Pentenoic acid, 2-acetyl-5-phenyl-, methyl ester, (E)-
• CAS NO: 85217-77-2
• Molecular Formula: C14H16O3
• Molecular Weight: 232.279
• Mol File: 85217-77-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4-Pentenoic acid, 2-acetyl-5-phenyl-, methyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 2-acetyl-5-phenyl-, methyl ester, (E)-(85217-77-2)
• EPA Substance Registry System: 4-Pentenoic acid, 2-acetyl-5-phenyl-, methyl ester, (E)-(85217-77-2)

Safety Data

• Hazardous Substances Data: 85217-77-2(Hazardous Substances Data)

Upstream product

• 105-45-3 acetoacetic acid methyl ester 
• 4392-24-9 Cinnamyl bromide 
• 21040-45-9 Cinnamyl acetate 
• 106625-69-8 ethyl (E)-3-phenyl-2-propenyl carbonate 
• 7217-71-2 1-phenyl-2-propenyl acetate 
• 34284-28-1 methyl acetoacetate, monosodium salt 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 673-32-5 1-Phenylprop-1-yne 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 16519-25-8 (E)-cinnamyl phenyl ether 
• 78-95-5 chloroacetone 
• 106625-70-1 ethyl (1-phenylallyl) carbonate 
• 87802-71-9 (E)-methyl cinnamyl carbonate 

Downstream Products

• 420089-28-7 (2E,4E)-5-Phenyl-penta-2,4-dienoic acid methyl ester 
• 1417719-33-5 (1S,2S,3R)-methyl 2-phenylbicyclo[1.1.0]butane-1-carboxylate 
• 1417719-34-6 (1R,2R,3S)-methyl 2-phenylbicyclo[1.1.0]butane-1-carboxylate 
• 38447-05-1 methyl (2Z,4E)-5-phenylpenta-2,4-dienoate 
• 176437-60-8 (E)-methyl 2-diazo-5-phenylpent-4-enoate 
• 88579-91-3 4-Hydroxy-2-methyl-3-phenyl-cyclopent-2-enecarboxylic acid methyl ester 

Relevant articles and documents

Monoallylation and benzylation of dicarbonyl compounds with alcohols catalysed by a cationic cobalt(iii) compound

Monoallylation and monoalkylation of diketones and β-keto esters with allylic and benzylic alcohols catalysed by [Cp*Co(CH3CN)3][SbF6]2(I) are reported. The method does not require any additive and affords regioselective products. The mechanistic investigations were done byin situ1H NMR spectroscopy as well as control experiments. It has been shown that reactions proceedviaη3-allyl complex formation or ally ether intermediate. The alkylation takes placeviaonly ether intermediate. The resulting allylated and alkylated products have been used for the synthesis of eleven new trisubstituted pyrazoles and one pyrazolone.

Construction of All-Carbon Quaternary Centers through Cu-Catalyzed Sequential Carbene Migratory Insertion and Nucleophilic Substitution/Michael Addition

A Cu-catalyzed three-component cross-coupling reaction of terminal alkyne, α-diazo ester, and alkyl halide has been developed. This transformation involves sequent migratory insertion of copper-carbene and nucleophilic substitution, in which a C(sp)-C(sp3) bond and a C(sp3)-C(sp3) bond are formed successively on a carbenic center. Michael addition acceptors can also be employed instead of alkyl halides that enable Michael addition to be an alternative way to build C(sp3)-C(sp3) bond. This transformation represents a highly efficient method for the construction of all-carbon quaternary centers.

Straightforward synthesis of allylated keto esters: The palladium-catalysed haloketone alkoxycarbonylation/allylation domino reaction

The palladium-catalysed α-chloro ketone methoxycarbonylation and allylic alkylation reactions can be efficiently combined to provide a new catalytic domino reaction. The first, carbonylative, step generates the β-keto ester, which acts as the nucleophile in a subsequent allylation step. The use of allyl phenates in combination with Xantphos ligand are the key features allowing one to obtain the allylated β-keto esters in good yields Copyright