85363-04-8

Basic information

• Product Name: N-(tert-Butoxycarbonyl)-2-aminoacetonitrile
• Synonyms: N-(TERT-BUTOXYCARBONYL)-2-AMINOACETONITRILE;BOC-2-AMINOACETONITRILE;BOC-GLY-NITRILE;AKOS 91568;Carbamic acid, (cyanomethyl)-, 1,1-dimethylethyl ester (9CI);N-BOC-2-Aminoacetonitrile;2-(Boc-aMino)acetonitrile;N-(tert-Butoxycarbonyl)-2-aminoacetonitrile 97%
• CAS NO: 85363-04-8
• Molecular Formula: C₇H₁₂N₂O₂
• Molecular Weight: 156.18
• Product Categories: N-BOC;C6 to C7;Cyanides/Nitriles;Nitrogen Compounds
• Mol File: 85363-04-8.mol
• Article Data: 22

Chemical Properties

• Melting Point: 53-57 °C(lit.)
• Boiling Point: 186 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.1832 (rough estimate)
• Refractive Index: 1.4880 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 9.96±0.46(Predicted)
• CAS DataBase Reference: N-(tert-Butoxycarbonyl)-2-aminoacetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-Butoxycarbonyl)-2-aminoacetonitrile(85363-04-8)
• EPA Substance Registry System: N-(tert-Butoxycarbonyl)-2-aminoacetonitrile(85363-04-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• WGK Germany: 3
• Hazardous Substances Data: 85363-04-8(Hazardous Substances Data)

Usage

Description

N-(tert-Butoxycarbonyl)-2-aminoacetonitrile is an organic building block that serves as a key intermediate in the synthesis of various organic compounds.

Uses

Used in Pharmaceutical Industry:
N-(tert-Butoxycarbonyl)-2-aminoacetonitrile is used as a synthetic intermediate for the preparation of N-(tert-butoxycarbonyl)-2-aminoacetamidoxime, which is an important compound in the pharmaceutical industry. N-(tert-Butoxycarbonyl)-2-aminoacetonitrile can be synthesized by reacting N-(tert-Butoxycarbonyl)-2-aminoacetonitrile with hydroxylamine hydrochloride.
Used in Organic Synthesis:
N-(tert-Butoxycarbonyl)-2-aminoacetonitrile is used as a versatile building block in organic synthesis for the preparation of a wide range of organic compounds. Its unique structure allows for various chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 6011-14-9 2-aminoacetonitrile hydrochloride 
• 35150-09-5 N-(tert-butoxycarbonyl)glycine 
• 4530-20-5 BOC-glycine 
• 22821-76-7 4-(methylsulfonyl)benzonitrile 
• 172876-96-9 3-oxo-1λ³-benzo[d][1,2]iodaoxole-1(3H)-carbonitrile 
• 151-63-3 cyanomethylamine sulfate 
• 51779-32-9 iminodicarboxylic acid di-tert-butyl ester 

Downstream Products

• 218164-28-4 Boc-Aca-OH 
• 540-61-4 2-aminoacetonitrile 
• 71904-80-8 2-((tert-butoxycarbonylamino)methyl)thiazole-4-carboxylic acid 
• 115894-70-7 tert-butyl ((2H-tetrazol-5-yl)methyl)carbamate 
• 1373278-78-4 methyl 5-(7-(5-((tert-butoxycarbonylamino)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate 
• 1360686-98-1 tert-butyl ((3-tert-butyl-1-(3-chlorophenyl)-1H-1,2,4-triazol-5-yl)methyl)carbamate 
• 479079-15-7 tert-butyl 2-(hydroxyamino)-2-iminoethylcarbamate 
• 479079-15-7 tert-butyl [(2Z)-2-amino-2-(hydroxyimino)ethyl]carbamate 
• 930272-56-3 2-(tert-butoxycarbonyl-aminomethyl)-5-methylpyrimidine 
• 85363-08-2 4-{(S)-2-[(6-{[Benzyloxycarbonyl-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-pyridine-2-carbonyl)-amino]-2-methoxycarbonyl-ethyl}-imidazole-1-carboxylic acid benzyl ester 
• 486402-88-4 (1-benzyl-1H-tetrazol-5-ylmethyl)-carbamic acid tert-butyl ester 
• 479079-15-7 tert-butyl [2-amino-2-(hydroxyimino)ethyl]carbamate 

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